PREPARATION OF BONE TUMOR THERAPEUTIC RADIOPHARMACEUTICALS ^153 Sm—EDTMP

ＰＲＥＰＡＲＡＴＩＯＮ　ＯＦ　ＢＯＮＥ　ＴＵＭＯＲ　ＴＨＥＲＡＰＥＵＴＩＣ　ＲＡＤＩＯＰＨＡＲＭＡＣＥＵＴＩＣＡＬＳ　~（１５３）Ｓｍ－ＥＤＴＭＰＬｕｏＳｈｕｎｚｈｏｎｇ（罗顺忠）；ＰｕＭａｎｆｅｉ（蒲满飞）；ＱｉａｏＪｉａｎ（谯健）；ＬｉｕＺｈｏｎ?..     

Electron microscopic observations and DNA chain fragmentation studies on apoptosis in bone tumor cells induced by ~(153)Sm-EDTMP

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燃气表无线抄表系统的设计与实现

针对现在抄表系统复杂度高或成本高等问题,本文设计了一套燃气表无线抄表系统,从基本架构、主要功能、软硬件的实现加以说明,具有实时、可靠、经济、低功耗等优点.该系统采用M430F413和EM78P153S为控制单元,CC1100为无线通信单元.该系统稳定可靠,具有良好的应用和推广价值.     

Patterns for multigrid equidistributed functions: Application to general parabolas and length estimation

We show that for some special functions (called k-multigrid equidistributed functions), we can compute the limit of the frequency of patterns in the discretization of their graph, when the resolution tends to zero. This result is applied to parabolas. We deduce also that local length estimators almost never converge to the length for the parabolas.     

On delay-derivative-dependent stability of systems with fast-varying delays

Stability of linear systems with uncertain bounded time-varying delays is studied under the assumption that the nominal delay values are not equal to zero. An input-output approach to stability of such systems is known to be based on the bound of the L₂-norm of a certain integral operator. There exists a bound on this operator norm in two cases: in the case where the delay derivative is not greater than 1 and in the case without any constraints on the delay derivative. In the present note we fill the gap between the two cases by deriving a tight operator bound which is an increasing and continuous function of the delay derivative upper bound d?1. For d→∞ the new bound corresponds to the second case and improves the existing bound. As a result, for the first time, delay-derivative-dependent frequency domain and time domain stability criteria are derived for systems with the delay derivative greater than 1.     

~(153)Sm-纳米羟基磷灰石的合成及生物行为初探

合成了纳米羟基磷灰石,制备的153Sm-EDTMP-nanoHA和153Sm-citrate-nanoHA体外稳定性良好。153Sm-EDTMP-nanoHA新西兰兔显像对比度较好,骨骼系统显示清晰,肝脾显影清晰,肾脏显影,血清除快;153Sm-citrate-nanoHA新西兰兔显像,肝脾显影清晰,血清除快,肾脏几乎不显影,说明主要通过肝胆排泄。153Sm-EDTMP-nanoHA对肝癌SMMC-7721和乳腺癌MCF-7细胞的半抑制率浓度分别是1.98g/L和0.075g/L,153Sm-citrate-nanoHA则分别是1.89g/L和0.094g/L。153Sm-EDTMP-nanoHA和153Sm-citrate-na-noHA较同等浓度下的单一nanoHA的半抑制率浓度低得多,具有很高的深入研究价值。     

153Sm-葡庚糖酸钠的制备

研究了制备条件对153Sm标记GH的影响及标记物的体外稳定性,建立了有效的153Sm标记葡萄糖酸钠(GH)方法。结果表明:用通氮敞开体系、沸水浴加热的标记方法,反应时间不低于30min,GH浓度不低于2.4×10-2mol/L时,可获得标记率大于98%的153Sm-GH;用高比活度153Sm(～4.5TBq/g(Sm))标记,其比活度可达14GBq/g(GH)。该标记物在室温下具有较好的稳定性,放置40h内,其放化纯度>96%。     

一种基于车载MP3播放机的倒车雷达设计

提出了一种基于车载MP3播放机-SH252的倒车雷达设计方案,并介绍了系统的软硬件设计思路。系统采用EM78P153单片机作为倒车雷达数据采集部分,采用超声波探测方式测距。在倒车时,倒车雷达会自动启动,并在EM78P153的控制下,由装置于车尾保险杠上的探头发送超声波信号,当遇到障碍物时,产生回波信号,探头接收到回波信号后经控制器进行数据处理并计算出车体与障碍物之间的实际距离,然后将数据发送到车载MP3播放机上进行距离显示和语音同步提示,为驾驶员提供报警提示,提高驾驶的安全性。     

153Sm标记二膦酸配体及其在羟基磷灰石上的吸附

制备了新的伯胺二膦酸类配体ABDP(4-氨基-1-羟丁基-1，1-二膦酸)和2-AEDP(2-氨基-亚乙基-1，1-二膦酸)的^153Sm标记物，研究其标记条件及体外性质。实验表明，使用^153Sm标记两个配体，其标记率均可以达到95％以上，增加配体量可以提高标记率和稳定性，通过研究标记物在羟基磷灰石(HA)上的吸附可以看出，^153Sm—ABDP在HA上的吸附率较高，提示它可能有较好的骨吸附。     

^153Gd骨密度计源的研制

本文介绍了生产~(153)Gd骨密度计源的原理、工艺和结果。采用天然Eu_2O_3作靶材料,汞阴极电解法分离得的~(153)Gd,经压制、烧结法制成源芯体。源的活度>3.7×10~10Bq,放射性核纯度>99.99%。