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1.
To improve the convertibility of reconfigurable manufacturing system (RMS), the concept of delayed reconfigurable manufacturing system (D-RMS) was proposed. RMS and D-RMS are both constructed around part family. However, D-RMS may suffer from ultra-long system problem with unacceptable idle machines using generic RMS part families. Besides, considering the complex basic system structure of D-RMS, machine selection of D-RMS should be addressed, including dedicated machine, flexible machine, and reconfigurable machine. Therefore, a system design method for D-RMS based on part family grouping and machine selection is proposed. Firstly, a part family grouping method is proposed for D-RMS that groups the parts with more former common operations into the same part family. The concept of longest relative position common operation subsequence (LPCS) is proposed. The similarity coefficient among the parts is calculated based on LPCS. The reciprocal value of the operation position of LPCS is adopted as the characteristic value. The average linkage clustering (ALC) algorithm is used to cluster the parts. Secondly, a machine selection method is proposed to complete the system design of D-RMS, including machine selection rules and the dividing point decision model. Finally, a case study is given to implement and verify the proposed system design method for D-RMS. The results show that the proposed system design method is effective, which can group parts with more former common operations into the same part family and select appropriate machine types. 相似文献
2.
The cyclooxygenase-2 (COX-2) is a potent enzyme that converts arachidonic acid to prostaglandins (PG), including PGE2, a key mediator of inflammation and angiogenesis. Importantly, COX-2 is activated in response to inflammatory stimuli, where it is also believed to promote the development and progression of head and neck cancers (HNC). COX-2 can mediate its protumorigenic effect through various mechanisms, such as inducing cell proliferation, inhibition of apoptosis, and suppressing the host’s immune response. Furthermore, COX-2 can induce the production of vascular endothelial growth factors, hence, promoting angiogenesis. Indeed, the ability of COX-2 inhibitors to selectively restrict the proliferation of tumor cells and mediating apoptosis provides promising therapeutic targets for cancer patients. Thus, in this comprehensive review, we summarized the reported differential expression patterns of COX-2 in different stages of head and neck carcinogenesis—from potentially premalignant lesions to invasive carcinomas. Furthermore, we examined the available meta-analysis evidence for COX-2 role in the carcinogenesis of HNC. Finally, further understanding of the biological processes of COX-2 and its role in orchestrating cell proliferation, apoptosis, and angiogenesis may give therapeutically beneficial insight to develop the management plan of HNC patients and improve their clinical outcomes. 相似文献
3.
Differences between oculomotor and perceptual artifacts for temporally limited head mounted displays
Alexander Goettker Kevin J. MacKenzie T. Scott Murdison 《Journal of the Society for Information Display》2020,28(6):509-519
We used perceptual and oculomotor measures to understand the negative impacts of low (phantom array) and high (motion blur) duty cycles with a high‐speed, AR‐likehead‐mounted display prototype. We observed large intersubject variability for the detection of phantom array artifacts but a highly consistent and systematic effect on saccadic eye movement targeting during low duty cycle presentations. This adverse effect on saccade endpoints was also related to an increased error rate in a perceptual discrimination task, showing a direct effect of display duty cycle on the perceptual quality. For high duty cycles, the probability of detecting motion blur increased during head movements, and this effect was elevated at lower refresh rates. We did not find an impact of the temporal display characteristics on compensatory eye movements during head motion (e.g., VOR). Together, our results allow us to quantify the tradeoff of different negative spatiotemporal impacts of user movements and make subsequent recommendations for optimized temporal HMD parameters. 相似文献
4.
主要探讨了某石化装置蒸汽发生系统的仪表工程设计,提出了复杂控制方案、联锁方案设计,同时也详述了影响系统设计的因素,如测量补偿和迁移等。 相似文献
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6.
于金辉 《计算机辅助设计与图形学学报》1994,6(3):181-185
本文提出一个用于计算机动画的转头模型。它利用头部的正面和侧面形象来构造出头的三维结构形象,然后按指定的旋转轴旋转该结构,经过边缘轮廓提取及隐线消除,最终得到正确的转头过程序列画面。 相似文献
7.
评述了ISO 5 75 5“烧结金属材料—规范”和美国MPIF标准 35的变迁和趋向统一。阐述了“最小强度值”的意义。说明了我国粉末冶金结构零件材料标准的现状 相似文献
8.
有水气藏是天然气藏中的一个基本气藏类型,其采收率受多种因素的影响,如地面集输压力、井筒混合气水流动的液柱压力和储层物性等,目前普遍采用经验取值、物质平衡和气藏数值模拟等方法进行研究,但由于受开发评价阶段试采资料偏少和气藏数值模拟无法模拟井筒流动等因素的影响,早期采收率计算往往偏差较大,针对这些问题,从气田开发一体化的特点出发,提出了一种全面考虑地层→井筒→地面流动条件下,有水气藏(含凝析有水气藏)发废弃压力的计算方法,发展了利用物质平衡早期预测有水气藏采收率的理论,方法可靠、适用性强,能够推广应用。 相似文献
9.
针对深孔钻机水刹车传动机构原设计结构中存在的问题进行分析、研究、并对机构进行了改进,满足了钻机绞车的各项性能指标和技术要求。 相似文献
10.