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Tolulope Joshua Ashaolu 《International Journal of Food Science & Technology》2021,56(8):3719-3725
Fervid interests on nanoparticles are increasing within the scientific and non-scientific communities, as they are utilised in food and non-food applications. The versatility of emerging applications of nanoparticles makes them potentially harmful to the food, healthcare and environment sectors, and thus necessitates the development of nanonutraceuticals from nutritional substances such as antioxidants, vitamins, fatty acids, fibres, probiotics and prebiotics. This review excavated state of the art on nanotechnology applications such as gold and selenium particles, nanolayers, nanobeads, nanoemulsions and nanofibers to probiotics and prebiotics for the synthesis of anticancer, antimicrobial, antioxidant and photo-reactive products among others, and finally delved into other noteworthy considerations like safety. It is concluded that available literature on the current status of nanoprobiotics and prebiotics are exhaustive, despite their huge potentials and applications. 相似文献
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王普善 《精细与专用化学品》2001,9(10):12-15
世界天然药物市场主要集中在美国、欧洲和亚洲三大区域,全球植物药市场的年销售额已达270亿美元。在过去的10年间,以植物制剂为主体的天然药物开始走俏西方。面对“回归自然”的世界潮流,采用现代科学技术,实现中药现代化和国际化,将为人类现代医疗保健做出重大贡献。 相似文献
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Cristian Dima Elham Assadpour Stefan Dima Seid Mahdi Jafari 《Comprehensive Reviews in Food Science and Food Safety》2020,19(3):954-994
Nowadays, many consumers prefer foods with a high content of nutraceuticals that contribute to the prevention or healing of chronic diseases. Therefore, in recent years, more and more researchers have studied the bioefficiency, safety, and toxicity of nutraceutical‐enriched foods. The key stage of nutraceutical bioefficiency is oral bioavailability, which involves the following processes: the release of nutraceuticals from food matrices or nanocarriers in gastrointestinal fluids, the solubilization of nutraceuticals and their interaction with other components of gastrointestinal fluids, the absorption of nutraceuticals by the epithelial layer, and the chemical and biochemical transformations into epithelial cells. These processes are endogenous factors that greatly influence the bioavailability of nutraceuticals. In addition to endogenous factors, the bioavailability of nutraceuticals is also affected by exogenous factors, such as: physicochemical properties of nutraceuticals, food matrix, food processing and storage, and so forth. Both the endogenous and exogenous factors are comprehensively analyzed in this review. Thus, the physicochemical and enzymatic processes involved in food digestion are described, highlighting the role of each stage of gastrointestinal tract (mouth, stomach, and intestine) in nutraceuticals bioaccessibility. The structure and functions of the mucus and epithelial layers, the mechanisms involved in the active and passive transport of nutraceuticals through the cell membrane, and phase I and phase II metabolism reactions are also discussed. Finally, this review focuses on several types of bioactive‐loaded nanocarriers such as lipid‐based, surfactant‐based, and biopolymeric nanocarriers that improve the bioavailability of nutraceuticals. 相似文献
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Preparation and optimisation of liposome‐in‐alginate beads containing oyster hydrolysate for sustained release
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Cheng‐liang Xie Su‐Seon Lee Se‐young Choung Sang Soo Kang Yeung Joon Choi 《International Journal of Food Science & Technology》2016,51(10):2209-2216
Oyster (Crassostrea gigas) hydrolysate shows antihypertensive effect in our previous study. Oral administration of oyster hydrolysate can loss bioactive peptides due to enzymatic degradation in vivo. To maximise its bioavailability, liposome‐in‐alginate (LA) beads were used to encapsulate the oyster hydrolysates to protect from degradation and obtain sustained release. The preparation conditions of the LA beads were optimised by response surface method using a model peptide of tyrosylalanine (YA). Their characterisation, swelling and release properties were investigated. The optimised conditions for the concentration of calcium chloride, sodium alginate and the amount of ethanol‐dissolved lecithin (EDL) were 0.5 m , 3% and 95.4 mg, respectively. The encapsulation efficiencies of YA and the oyster hydrolysate in the optimised condition were 74.9% and 84.3%, respectively. The release time of the oyster hydrolysate in the simulated gastrointestinal fluid was up to 16 h. The LA beads can be recommended to encapsulate oyster hydrolysate for bioavailability improvement. 相似文献
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Gracia Fahed Laurence Aoun Morgan Bou Zerdan Sabine Allam Maroun Bou Zerdan Youssef Bouferraa Hazem I. Assi 《International journal of molecular sciences》2022,23(2)
Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis of MetS encompasses multiple genetic and acquired entities that fall under the umbrella of insulin resistance and chronic low-grade inflammation. If left untreated, MetS is significantly associated with an increased risk of developing diabetes and cardiovascular diseases (CVDs). Given that CVDs constitute by far the leading cause of morbidity and mortality worldwide, it has become essential to investigate the role played by MetS in this context to reduce the heavy burden of the disease. As such, and while MetS relatively constitutes a novel clinical entity, the extent of research about the disease has been exponentially growing in the past few decades. However, many aspects of this clinical entity are still not completely understood, and many questions remain unanswered to date. In this review, we provide a historical background and highlight the epidemiology of MetS. We also discuss the current and latest knowledge about the histopathology and pathophysiology of the disease. Finally, we summarize the most recent updates about the management and the prevention of this clinical syndrome. 相似文献
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Nanoscale Nutrient Delivery Systems for Food Applications: Improving Bioactive Dispersibility,Stability, and Bioavailability
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David Julian McClements 《Journal of food science》2015,80(7):N1602-N1611
There has been a surge of interest in the development of nanoscale systems for the encapsulation, protection, and delivery of lipophilic nutrients, vitamins, and nutraceuticals. This review article highlights the challenges associated with incorporating these lipophilic bioactive components into foods, and then discusses potential nanoscale delivery systems that can be used to overcome these challenges. In particular, the desirable characteristics required for any nanoscale delivery system are presented, as well as methods of fabricating them and of characterizing them. An overview of different delivery systems is given, such as microemulsions, nanoemulsions, emulsions, microgels, and biopolymer nanoparticles, and their potential applications are discussed. Nanoscale delivery systems have considerable potential within the food industry, but they must be carefully formulated to ensure that they are safe, economically viable, and effective. 相似文献
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