超声引导下肝细胞癌穿刺组织中Ezrin表达的临床意义

探讨Ezrin表达及超声引导下穿刺活检对肝细胞癌（HCC）的应用价值,实验方法如下：36例经超声引导下穿刺所得的HCC组织作肝穿癌组;45例手术切除的HCC组织作手术癌组,同时取12个癌旁肝组织作癌旁组;用免疫组化方法检测两组标本的Ezrin蛋白表达,并与临床病理学参数做统计学分析。得出结果：肝穿癌组Ezrin阳性表达...     

The murine plasma protein response to polymicrobial intra-abdominal sepsis

Protein biomarkers in the peripheral blood could potentially be used as early indicators of sepsis and a means to stratify patients for clinical trials. Although individual molecular markers have been proposed for sepsis, none has clinical utility. The global changes in plasma proteins over the clinical course of sepsis have not been characterized using proteomic methods. We used cecal ligation and puncture to induce polymicrobial sepsis in mice and generated plasma protein profiles using 2‐D DIGE of plasma from septic mice and surgical controls. Replicate cohorts (n = 3) of 4–7 animals each were used to identify 62 gel features that changed significantly (Student's t‐test, p<0.05). We identified a suite of plasma proteins that describe uniquely the host plasma response to polymicrobial septic insult. Principal components analysis of protein abundance showed that ～90% of the variability between samples was due to sepsis. In addition to canonical acute phase proteins, we identified proteins that are associated with metabolic changes (e.g. α‐2 HS glycoprotein and zinc α‐2 glycoprotein) consistent with the pathophysiology of sepsis. The panel of sepsis‐associated molecular markers identified herein may prove useful in the diagnosis and categorization of sepsis.     

Probabilistic analysis of geomembrane puncture from granular material under liquid pressure

A simplified probabilistic analysis of geomembrane punctures from granular material was presented when subjected to liquid pressure. The probability distribution of contact force between geomembrane and granular material was obtained based on the principle of equal probability and assumptions that grains are spheres with constant size. A particle flow code PFC^3D was employed to simulate the contact process which indicates a good agreement with the theoretical probabilistic analysis. The odds of geomembrane puncture from grains of constant size were obtained by evaluating the puncture force which should not exceed the puncture resistance of geomembrane. The effects of grain radius, grain rigidity and liquid pressure were studied in more detail and displayed in graphs. Both high-level of liquid pressure and large grain can result in high risk of geomembrane puncture. The influence of grain rigidity on the geomembrane puncture odds is significant. For granular material with a grain size distribution, the geomembrane puncture odds can be estimated by the grain size distribution, served as weight function and it is a cautious design if the largest grain is chosen as the design grain size.     

关于环氧树脂粘接瓷绝缘件接口电击穿问题的探讨

通过对耐压检查过程的分析以及对粘接过程的模拟观察,确定了击穿的主要原因是接口胶层内存在气隙。根据所用环氧树脂粘接剂的粘度,适当提高粘接面的预热温度和粘接前粘接剂涂层的厚度,有利于粘接时封闭空气的排除,有利于减少气隙,从而减少击穿。同时证明,两瓷件接口面对接后,转动瓷件的作用是排胶。转动幅度不能过大,尽量不要使两接口面错开,以免再次产生气隙。     

一种整体较优的RCPT码删除矩阵新算法

由于无线信道的时变、高误码等特性，要求信道编码方式不仅具有较强的抗误码能力，而且能够自适应的调整码率来适应无线信道状态的变化．码率可变的RCPT码能够实现这样的编码要求，但是RCPT码的编译码性能取决于其删除矩阵的选取．针对这一问题综合国内外的研究现状，提出了一种整体较优的求取RCPT码删除矩阵的新算法．这种算法利用不同删除矩阵求取算法的不同适用性，达到了在高、低码率下都能够取得较好编译码效果的目的．     

无线信道图像的联合信源信道编码速率分配

分析了信源信道编码速率对图像质量的影响，提出一种联合信源信道编码的速率分配方案。针对渐进图像的速度分配疸建立了数学模型，对模型的求解进行了简化，并采用拉格朗日乘数法，在满足一定的约束条件下实现了速度的最优化分配。在瑞利及Gilbert-Elliot信道下的仿真结果表明，该方案在低信噪比时的性能明显优于固定信道方法，在高信噪比时也较固定信道速率方法有0.2dB左右的性能增益。     

铝电解电容器芯包引脚刺孔机控制系统设计

针对目前铝电解电容器芯包引脚刺孔中存在的自动化程度低、劳动强度大等不足,设计了铝电解电容器芯包引脚刺孔机控制系统,并提供了电气硬件和软件系统设计方案.该系统以三菱FGA系列PLC为核心,结合步进电机、振动盘、气缸以及光纤传感器和位置传感器等元件的检测定位,实现华司自动上料、芯包移动、引脚刺孔、芯包翻转等工序的自动连续运行.现场调试运行表明:该系统运行可靠平稳,操作简单,劳动强度低,能够满足生产线高效率、高质量的自动化加工要求.     

基于IP核的Viterbi译码器实现

Viterbi译码器在通信系统中应用非常普遍,针对采用DSP只能进行相对较低速率的Viterbi译码的问题,人们开始采用FPGA实现高速率Viterbi译码。本文首先简单描述了Viterbi译码的基本过程,接着根据Viterbi译码器IP核的特点,分别详细介绍了并行结构、混合结构和基于混合结构的增信删余3种Viterbi译码器IP核的主要性能和使用方法,并通过应用实例给出了译码器IP核的性能仿真。     

Seldinger技术改良法单人置鞘操作流程的探讨

Seldinger技术是血管内介入性诊疗需涉及的技术,其改良法更具优点,加之器械应用的改进,使得单人置管成为可能。探讨此技术的操作流程有助于在临床顺利开展血管内介入放射治疗术,实践证明此方法不仅简便易行,定位准确,而且置管可靠,少有不良反应及严重损伤。