Estimates of pollutant temporal and spatial variability in commercial buildings from the joint urban 2003 field experiments

In this paper, we report on the indoor concentrations from a suite of full-scale outdoor tracer-gas point releases conducted in the downtown area of Oklahoma City in 2003. A point release experiment consisted of releases of sulfur hexafluoride (SF₆) in multiple buildings and from different outdoor locations. From the measurements, we are able to estimate the concentration variations indoors for a building operating under “typical” operating conditions. The mean indoor spatial coefficients of variation are 30% to 45% from a daytime outdoor release are around 80% during an outdoor evening release. Having estimates of the spatial coefficient of variation provides stakeholders, including first responders, with the likely range of concentrations in the building when little is known about the building characteristics and operating behavior, such as developing urban-scale hazard and consequence analyses. We show differences in indoor measurements at different distances to the release points, floors of the building, and heating, ventilation, and air conditioning system (HVAC) operation. We also show estimates at different time resolutions. The statistics show that in the studied medium to large commercial buildings, spatial differences would result in peak indoor concentrations in certain parts of the buildings that may be substantially higher than the building average. To our knowledge, very few tracer gas measurements have been conducted in buildings of this scope, particularly with measurements on multiple floors and within a floor. The resulting estimates of spatial variability provide a unique opportunity for hazard assessment, and comparison to multi-zone models.     

Development and monitoring of an integrated bioprocess for production of a potential malaria vaccine with Pichia pastoris

An engineered variant of the yeast Pichia pastoris was used to produce the potential malaria vaccine D1M1. This paper describes the implementation of an expanded bed adsorption chromatography step into a sequential cultivation process of the yeast in order to link protein expression, cell release, and product capture of the secreted protein in a fully automated plant. The process is operated with a semi-continuous strategy for an integrated production. Process improvements have been achieved using design of experiments. Resulting purities of product achieved up to 87% with recoveries of 51% in a single downstream operation. Furthermore, a multivariate analysis of historical batch data was used to develop a golden batch model for process monitoring.     

大型结构试验和结构监测中的数据采集系统

结构试验和结构监测正在向大型化和复杂化发展,与之配套的数据采集系统也要能满足它们不断增长的需求。清华大学土木工程系开发了适用于土木工程结构试验与监测的集成数据采集系统 IMPDAS,它具有测点多,速度快,功能全等优点。它的任务,不仅仅是记录数据,而是集成并且管理数据,将各种数据信息有条理,有重点地反馈给试验者。本文将讨论计算机在大型结构试验和结构监测的数据采集及数据处理分析等方面的应用。     

Prediction Model for BTA Deep-Hole Machining using Fuzzy Clustering Approach: Experimental Study

In this article, a subtractive clustering-based fuzzy identification method and a Sugeno-type fuzzy inference system are used for modeling in metal cutting. This approach is considered with its application on the experimental study of Boring and Trepanning Association (BTA) deep-hole drilling. The model for the surface roughness is identified by using the cutting speed and feed as input data and roughness as the output data. Using subtractive clustering in both input and output spaces performs the model-building process. Minimum error model is obtained through enumerative search of clustering parameters. The fuzzy model obtained is capable of predicting the surface roughness for a given set of inputs (speed and feed). Therefore, the operator can predict the quality of the surface for a given set of working parameters and will then be able to set the machining parameters to achieve a certain surface quality. The fuzzy model is verified experimentally by further experimentation using different sets of inputs. The tool life is also investigated using the same approach. The fuzzy inference system obtained is capable of predicting the tool life for a given set of cutting parameters. Therefore, the operator will be able to predict how many minutes the cutting tool is going to last and will set the time for the next tool change.     

JFC磷酸酯的合成和应用

详述了JFC磷酸酯的合成工艺路线，以及它在织物前处理精练工艺中的应用。与其它磷酸酯类精练剂性能对比，证明它可作为一种性能优良的精练剂中的添加剂。     

High temperature controlled atmosphere experiments for catalysts in a transmission electron microscope

A new transmission electron microscopy (TEM) specimen preparation procedure for high temperature experiments using a controlled atmosphere specimen holder (HTCASH) has been developed. It is designed for studying the microstructure of catalyst specimens before and after treatments in various gases. The procedure involved (1) finding a new formula for the embedding material, (2) devising a new method of making specimen supports, and (3) developing a method for removing the embedding material after the specimen has been microtomed. These techniques were then brought together to produce the ideal specimens for the HTCASH experiments. As an extra benefit, this procedure is also suitable for preparing specimens for ultrahigh resolution imaging experiments. The application of the new procedure in HTCASH experiments is illustrated through a high temperature reduction of a Co/SiO₂-923 catalyst.     

黄河黑山峡河段大柳树水库比小观音水库原始库容多40亿m3的作用

一级开发大柳树高坝原始库容比二级开发小观音高坝多 4 0亿m3 ,库容大带来的好处体现在 5～ 7月可多向下游增供水量 ,缓解下游河道断流 ;延长泄放清水时间 ;增加发电效益 ;满足宁蒙河段防凌要求 ;增加汛期集中泄水 ,减缓下游河道淤积萎缩 ;满足南水北调西线工程水量调节要求等。为了更好优化配置黄河水资源 ,从全局和长远利益考虑 ,应采用一级开发方案 ,修建大柳树高坝大库     

明渠水流泥沙运动水深平均及力矩方程的理论和验证

首次提出了水流泥沙运动水深平均及其力矩方程的概念 ,并从理论上推导出这套方程组。提出水流泥沙运动力矩方程的目的有两个 ,一是在不增加空间维数的情况下可以有效地恢复水流泥沙因子沿水深分布信息 ,克服目前普遍使用的水深平均方程过多地忽略沿水深分布信息的缺点 ;二是增强模型的模拟能力。针对这两个目的是否能真正得到体现 ,分别从理论和实验室资料两个方面对新推导的力矩方程进行了全面的检验。理论验证结果表明 ,一维的力矩方程除了能模拟水深平均的流速和含沙量 ,还能够较好地模拟水流泥沙因子沿水深分布信息 ,这充分说明了一维力矩方程的二维特性。为了检验力矩方程的模拟能力 ,特别选取了一些极端的水流泥沙运动实验 ,如清水冲刷、点源加沙和深槽回淤等。模拟结果表明 ,力矩方程对于这些极端的水沙运动具有较好的模拟能力