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1.
死亡风险预测指根据病人临床体征监测数据来预测未来一段时间的死亡风险。对于ICU病患,通过死亡风险预测可以有针对性地对病人做出临床诊断,以及合理安排有限的医疗资源。基于临床使用的MEWS和Glasgow昏迷评分量表,针对ICU病人临床监测的17项生理参数,提出一种基于多通道的ICU脑血管疾病死亡风险预测模型。引入多通道概念应用于BiLSTM模型,用于突出每个生理参数对死亡风险预测的作用。采用Attention机制用于提高模型预测精度。实验数据来自MIMIC [Ⅲ]数据库,从中提取3?080位脑血管疾病患者的16?260条记录用于此次研究,除了六组超参数实验之外,将所提模型与LSTM、Multichannel-BiLSTM、逻辑回归(logistic regression)和支持向量机(support vector machine, SVM)四种模型进行了对比分析,准确率Accuracy、灵敏度Sensitive、特异性Specificity、AUC-ROC和AUC-PRC作为评价指标,实验结果表明,所提模型性能优于其他模型,AUC值达到94.3%。 相似文献
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In the past, thinking of carrying electronic devices inside our bodies was only posed by non-real scenarios. The emergence of insertable devices has changed this. Since this technology is still in its initial development stages, few studies have investigated factors that influence its acceptance. This paper analyzes the predictors of the intention to use non-medical insertable devices in two Latin American contexts. We used partial least squares structural equation modeling to examine whether six constructs predicted intention to use insertable devices. A questionnaire was administered to undergraduate students located in Colombia and Chile (n = 672). We also examined whether these predictors influenced intention differently for both of them. Four common constructs significantly and positively influenced both Chilean and Colombian respondents to use insertable devices (hedonic motivation, habit, performance expectancy, and social influence). Also, the habit has a complementary mediating effect on the relationship between social influence and behavioral intention. By contrast, effort expectations were a positive and significant predictor, but only among Chilean respondents. Findings suggest that when technologies are emerging, well-known predictors of intention (e.g., performance and effort expectations) are less influential than predictors related to self-efficacy (e.g., habit and hedonic motivation). The use of insertable devices has a significant impact on society. Thus, a better understanding of what motivates their use has implications for both academia and industry. 相似文献
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为了开发β受体阻断剂新药(S)-噻吗洛尔半水合物,采用3-吗啉-4-氯-1,2,5-噻二唑为起始原料,经水解反应得到中间体1(3-吗啉-4-羟基-1,2,5-噻二唑)。中间体1与R-环氧氯丙烷发生醚化反应,经后处理及重结晶得到中间体2 {(R)-4-[4-(环氧乙烷-2-基甲氧基)-1,2,5-噻二唑-3-基]吗啉}。中间体2经胺化反应、马来酸成盐及重结晶得到(S)-马来酸噻吗洛尔。(S)-马来酸噻吗洛尔经游离、纯水转晶得到符合药典标准的(S)-噻吗洛尔半水合物,总收率14.05%且e.e.值为99.66%。最终成品经IR、1H-NMR、13C-NMR、MS、TGA、DSC表征,并优化各步反应条件。结果表明:以三乙胺为醚化反应缚酸剂75 ℃反应最佳;以乙醇为胺化反应溶剂46 ℃反应16 h最佳;S-噻吗洛尔的转晶拆分以水作溶剂,比传统不对称合成工艺安全稳定,操作简单,适合工业化生产。 相似文献
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High dimensionality in real-world multi-reservoir systems greatly hinders the application and popularity of evolutionary algorithms, especially for systems with heterogeneous units. An efficient hierarchical optimization framework is presented for search space reduction, determining the best water distributions, not only between cascade reservoirs, but also among different types of hydropower units. The framework is applied to the Three Gorges Project (TGP) system and the results demonstrate that the difficulties of multi-reservoir optimization caused by high dimensionality can be effectively solved by the proposed hierarchical method. For the day studied, power output could be increased by 6.79 GWh using an optimal decision with the same amount of water actually used; while the same amount of power could be generated with 2.59 × 107 m3 less water compared to the historical policy. The methodology proposed is general in that it can be used for other reservoir systems and other types of heterogeneous unit generators. 相似文献
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This article examines how older adults use and perceive digital technologies in Finland and Ireland. These two countries are at different stages regarding two important global trends – demographic ageing and digitalization. Finland, being the fastest ageing society in Europe, is also one of the leaders in implementing digital technologies in social and health care services. In contrast, Ireland is a demographically younger and less digitalized society. Drawing on focus group discussions on the usage of digital technologies, conducted with older adults in both countries, we analyse how digital technologies are adopted and viewed by older generations. The analyses showed that older adults associate digitalization with both advantages and drawbacks. To encapsulate these two contrasting aspects, we developed the term Janus-faced conceptions of technology. This concept encapsulates how the successful adoption of digital technology facilitates everyday activities whereas the inability to utilise technologies results in feelings of alienation and being out-of-touch. The digital divide was found to occur not only between generations but also between different socioeconomic groups of older adults. 相似文献
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通过分析A公司在研发项目范围管理中所存在问题,提出研发项目范围管理的方法及其在C产品的应用实例,通过运用研发项目范围管理的工具和方法,改善产品开发流程,从而缩短新产品开发周期,提高响应市场的速度,并提高企业研发项目的管理能力。 相似文献
9.
目前网络上的服装图像数量增长迅猛,对于大量服装图像实现智能分类的需求日益增加。将基于区域的全卷积网络(Region-Based Fully Convolutional Networks,R-FCN)引入到服装图像识别中,针对服装图像分类中网络训练时间长、形变服装图像识别率低的问题,提出一种新颖的改进框架HSR-FCN。新框架将R-FCN中的区域建议网络和HyperNet网络相融合,改变图片特征学习方式,使得HSR-FCN可以在更短的训练时间内达到更高的准确率。在模型中引入了空间转换网络,对输入服装图像和特征图进行了空间变换及对齐,加强了对多角度服装和形变服装的特征学习。实验结果表明,改进后的HSR-FCN模型有效地加强了对形变服装图像的学习,且在训练时间更短的情况下,比原来的网络模型R-FCN平均准确率提高了大约3个百分点,达到96.69%。 相似文献
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文章归纳了2020年电子电路产业一些技术热点,主要有5G电路板设计和基材,制造方面半加成法、3D打印、直接金属化孔电镀和垂直互连结构等技术,以及集成电路封装载板技术。 相似文献