剖析F型、GK型密炼机结构特征

目前，以美国F型和德国GK型为代表的密炼机已在我国基本上实现了国产化。对这两类密炼机的结构特点和安装、使用上的利与弊，本文从密炼装置、转子密封装置、卸料装置、锁紧装置到主传动5个方面作了详细的剖析，并在此基础上，提出一个取长补短的新的密炼机设计方案。     

VoIP认证与计费的设计与实现

基于RADIUS的VoIP认证系统，采用分散受理、集中管理的接入认证管理体系，数据集中存放在认证中心(RADIUS服务器)，用户身份认证由PC向网守发起，网守通过RADIUS协议向认证中心的认证服务器发起认证请求。这样，可以保证用户安全地使用网络资源，以确保用户身份的合法性。同时其落地话单经过处理，可进行计费及其它帐务处理。文中论述了RADIUS对VoIP的支持，提出了一个Gatekeeper与RADIUS结合的整体解决方案。     

基于微粒群优化的船舶柴油机T-S模糊模型

提出了一种基于微粒群优化(PSO)的T-S模糊模型的非线性系统辨识方法,并用于船舶柴油机的动态建模.该辨识方法采用GK模糊聚类算法确定模糊模型的前件结构及参数,利用PSO算法来辨识模糊模型的结论参数.利用6160-All船舶柴油机模型,获得柴油机各主要参数在油门尺度和负载发生小偏差扰动时的试验数据,再利用该组数据辨识出柴油机转速、涡轮增压器转速、增压压力、空冷器压力、进气管压力、排气管压力等参数的T-S模糊动态模型.仿真结果表明了该方法的有效性.     

神经模糊系统中模糊规则的优选

提出一种基于两级聚类算法的自组织神经模糊系统，该系统采用两级聚类算法（改进的最近邻域聚类算法和Gustafson-Kessel模糊聚类算法）对输入／输出数据进行模糊聚类，并由模糊聚类的划分熵确定最优划分，建立模糊模型，模型精度可由梯度下降法进一步提高。仿真结果表明，这种神经模糊系统具有结构简单、规则数少、学习速度快以及建模精度高等特点。     

一起罕见的GK1c型机车冷却风扇偶合器故障的分析与处理

介绍了GK1c型机车冷却风扇偶合器的概况及其常见故障现象和处理方法。针对一起罕见的泵轮轴断裂故障进行了系统分析，简单介绍了对此故障的处理方法，并提出了一些建议。     

Activated PPARβ/δ Protects Pancreatic β Cells in Type 2 Diabetic Goto–Kakizaki Rats from Lipoapoptosis via GPR40

GW501516-activated peroxisome proliferator-activated receptor (PPAR) β/δ and G-protein-coupled receptor (GPR) 40 were shown to protect pancreatic β cells against lipoapoptosis. Therefore, this study aimed to investigate whether activated PPARβ/δ could protect type 2 diabetic rats from lipoapoptosis through regulation of GPR40 and to compare the protective effects of activated PPARβ/δ and PPARγ. We made an animal model of type 2 diabetic lipoapoptosis by feeding spontaneously type 2 diabetic Goto–Kakizaki (GK) rats with a high-fat diet (HFD) to evaluate the effects of PPARβ/δ on islet β cell apoptosis. And, treated INS-1 cells with 0.5 mM palmitate (PAM) in the absence/presence of GW501516 (a specific agonist of PPAR β/δ) and with/without transfection of GPR40 siRNA to explore the underlying molecular mechanism. HFD aggravated GK rats' poorer INSR30, lower mass, greater apoptosis of β cells, lower mass, and lower expression of GPR40, which were similarly improved by GW501516 at 3 or 6 mg/kg day and pioglitazone. Compared with pioglitazone, GW501516 caused more weight loss and had no effect on insulin resistance. GW501516 protected INS-1 cells from PAM-induced apoptosis by upregulating GPR40 and activating Akt/Bcl-2/caspase-3. Activated extracellular regulated protein kinases (ERK) was relevant to the lipoapoptosis in INS-1 cells, but was not involved in the antilipoapoptotic effect of GW501516. These results showed that the PPARβ/δ agonist GW501516 protected β cells from lipoapoptosis and improved β cell mass by upregulating GPR40 and activating the Akt/Bcl-2/caspase-3 pathway, but not the ERK-signaling pathway.     

基于PLC实现的光电式纠偏系统

本文针对彩色印刷、印染等行业中存在的位置偏差问题,设计出了基于模糊控制思想的光电式纠偏系统。该系统用PLC作为核心控制器、GK112光电隔离器检测位置偏移量、三相步进电机驱动丝杠作为执行机构。通过实验证明了该系统有较高的实用性。     

GK型机车基础制动形式选择的探讨

通过对GK型机车两种制动形式的比较,对单、双侧制动的制动能力得出正确的结论,并对两种制动的优劣作出评述。认为:单侧制动方式能够很好地解决机车的闸瓦偏磨问题;如果采用合成闸瓦,则双侧制动时的制动力明显大于单侧制动时的制动力。     

基于UML的VOIP计费服务器的设计与实现

计费服务器是VOIP系统中十分重要的网络设备.它主要负责采集来自各GK节点的计费数据,并且对计费数据进行保存、校验、过滤、转换等各项预处理,然后将计费数据传输给计费系统进行最后的批价.如何进一步提高计费服务器稳定性,建立良好的故障处理机制,利用UML和C 技术开发基于Sun Solaris平台的计费服务器,通过设计系统的体系结构和协议处理流程,给出了一个好的解决方案.     

Dietary resistant starch improves selected brain and behavioral functions in adult and aged rodents

Resistant starch (RS) is a dietary fiber that exerts multiple beneficial effects. The current study explored the effects of dietary RS on selected brain and behavioral functions in adult and aged rodents. Because glucokinase (GK) expression in hypothalamic arcuate nucleus and area postrema of the brainstem is important for brain glucose sensing, GK mRNA was measured by brain nuclei microdissection and PCR. Adult RS‐fed rats had a higher GK mRNA than controls in both brain nuclei, an indicator of improved brain glucose sensing. Next, we tested whether dietary RS improve selected behaviors in aged mice. RS‐fed aged mice exhibited (i) an increased eating responses to fasting, a behavioral indicator of improvement in aged brain glucose sensing; (ii) a longer latency to fall from an accelerating rotarod, a behavioral indicator of improved motor coordination; and (iii) a higher serum active glucagon‐like peptide‐1 (GLP‐1). Then, GLP‐1 receptor null (GLP‐1RKO) mice were used to test the role of GLP‐1 in brain glucose sensing, and they exhibited impaired eating responses to fasting. We conclude that in rodents (i) dietary RS improves two important indicators of brain function: glucose sensing and motor coordination, and (ii) GLP‐1 is important in the optimal feeding response to a fast.