Advanced daytime polysomnographic preprocessing: A versatile approach for stream-wise estimation

The enhancement of monitoring biosignals plays a crucial role to thrive successfully computer-assisted diagnosis, ergo the deployment of outstanding approaches is an ongoing field of research demand. In the present article, a computational prototype for preprocessing short daytime polysomnographic (sdPSG) recordings based on advanced estimation techniques is introduced. The postulated model is capable of performing data segmentation, baseline correction, whitening, embedding artefacts removal and noise cancellation upon multivariate sdPSG data sets. The methodological framework includes Karhunen–Loève Transformation (KLT), Blind Source Separation with Second Order Statistics (BSS-SOS) and Wavelet Packet Transform (WPT) to attain low-order, time-to-diagnosis efficiency and modular autonomy. The data collected from 10 voluntary subjects were preprocessed by the model, in order to evaluate the withdrawal of noisy and artefactual activity from electroencephalographic (EEG) and electrooculographic (EOG) channels. The performance metrics are distinguished in qualitative (visual inspection) and quantitative manner, such as: Signal-to-Interference Ratio (SIR), Root Mean Square Error (RMSE) and Signal-to-Noise Ratio (SNR). The computational model demonstrated a complete artefact rejection in 80% of the preprocessed epochs, 4 to 8 dB for residual error and 12 to 30 dB in signal-to-noise gain after denoising trial. In comparison to previous approaches, N-way ANOVA tests were conducted to attest the prowess of the system in the improvement of electrophysiological signals to forthcoming processing and classification stages.     

Investigation of RF sputtered PSG films for MEMS and semiconductor devices

In this work, we report the preparation of phospho-silicate-glass (PSG) films using RF magnetron sputtering process and its application as a sacrificial layer in surface micromachining technology. For this purpose, a 76 mm diameter target of phosphorus-doped silicon dioxide was prepared by conventional solid-state reaction route using P₂O₅ and SiO₂ powders. The PSG films were deposited in a RF (13.56 MHz) magnetron sputtering system at 200-300 W RF power, 10-20 mTorr pressure and 45 mm target-to-substrate spacing without external substrate heating. To confirm the presence of phosphorus in the deposited films, hot-probe test and sheet resistance measurements were performed on silicon wafers following deposition of PSG film and a drive-in step. As a final confirmatory test, a p-n diode was fabricated in a p-type Si wafer using the deposited film as a source of phosphorus diffusion. The phosphorus concentration in the target and the deposited film were analyzed using energy dispersive X-rays (EDAX) tool. The etch rate of the PSG film in buffered HF was measured to be about 30 times higher as compared to that of thermally grown SiO₂ films. The application of RF sputtered PSG film as sacrificial layer in surface micromachining technology has been explored. To demonstrate the compatibility with MEMS process, micro-cantilevers and micro-bridges of silicon nitride were fabricated using RF sputtered PSG as a sacrificial layer in surface micromachining. It is envisaged that the lower deposition temperature in RF sputtering (<150 °C) compared to CVD process for PSG film preparation is advantageous, particularly for making MEMS on temperature sensitive substrates.     

Surface nanocrystalline Si structure and its surface passivation for highly efficient black Si solar cells

19.5% conversion efficiency crystalline silicon (Si) solar cells having simple structure without antireflection coating have been fabricated using the surface structure chemical transfer method which produces a nanocrystalline Si layer simply by contacting catalytic platinum with Si wafers in hydrogen peroxide plus hydrofluoric acid solutions. The reflectivity becomes less than 3% after the surface structure chemical transfer method due to formation of black Si. Deposition of phosphosilicate glass and heat treatment at 925 °C performed for formation of pn‐junction effectively passivate the nanocrystalline Si surface. With this phosphosilicate glass passivation plus the hydrogen treatment at 400 °C, the internal quantum efficiency is greatly improved and reaches 81% at a wavelength of 400 nm. Analysis of ellipsometry data shows that incident light with wavelength shorter than 400 nm is almost completely absorbed by the nanocrystalline Si layer. The high internal quantum efficiency for short wavelength light is attributed to effective surface passivation and the nanocrystalline Si layer band‐gap energy which decreases with the distance from the top of the network structure of the nanocrystalline Si layer. Copyright © 2017 John Wiley & Sons, Ltd.     

一种以多晶硅为振动膜的MEMS传声器研制

给出了以磷掺杂的多晶硅为振动膜的电容式MEMS传声器的研制过程。从等效电路模型出发,研究了电容式MEMS传声器的振动特性和灵敏度,给出了传声器灵敏度随振动膜张力、膜与背板间的空气隙厚度、背板声孔大小及背板声孔所占面积而变化的解析表达式。结合硼掺杂硅/硅复合背板结构MEMS传声器,提供了参考制作工艺流程。样品测试在1kHz频率处的灵敏度达到-60dB(相对于1V/Pa)。     

Longitudinal Proteomic Analysis of Plasma across Healthy Pregnancies Reveals Indicators of Gestational Age

Longitudinal changes in the blood proteome during gestation relate to fetal development and maternal homeostasis. Charting the maternal blood proteome in normal pregnancies is critical for establishing a baseline reference when assessing complications and disease. Using mass spectrometry-based shotgun proteomics, we surveyed the maternal plasma proteome across uncomplicated pregnancies. Results indicate a significant rise in proteins that govern placentation and are vital to the development and health of the fetus. Importantly, we uncovered proteome signatures that strongly correlated with gestational age. Fold increases and correlations between the plasma concentrations of ADAM12 (ρ = 0.973), PSG1 (ρ = 0.936), and/or CSH1/2 (ρ = 0.928) with gestational age were validated with ELISA. Proteomic and validation analyses demonstrate that the maternal plasma concentration of ADAM12, either independently or in combination with either PSG1 or CSH1/2, correlates with gestational age within ±8 days throughout pregnancy. These findings suggest that the gestational age in healthy pregnancies may be determined by referencing the concentration of select plasma proteins.     

单纯UPPP术治疗OSAHS远期疗效分析

目的探讨UPPP术治疗OSAHS的远期疗效。方法随访132例OSAHS患者。结果 68例疗效显著,64例疗效欠佳,有效率51.5%。结论术前准确地判断呼吸暂停综合征的类型及上气道阻塞平面对术式的选择尤其重要。     

MIC薄膜多晶硅材料的动态镍吸除技术基本机理及其应用

首先阐述了MIC薄膜多晶硅材料动态镍吸杂技术的基本机理和主要工艺过程,然后以多晶硅薄膜晶体管(poly-Si TFT)为例研究了动态吸杂技术的应用.在研究金属诱导晶化多晶硅材料(MIC poly-Si)和以之为有源层的poly-Si TFT的过程中,发现在MIC多晶硅薄膜中含有部分残余的镍成份.而大部分存在于对撞晶界的残余镍成份会造成大量的缺陷,这将导致TFT器件性能乃至整个系统的稳定性和可靠性的降低.为了改善MIC薄膜及器件质量,我们采用磷硅玻璃(PSG)动态镍吸杂技术,有效地吸除镍,降低多晶硅中镍的残留量,改善对撞晶界的缺陷密度,降低用之制备TFT的漏电流.该技术工艺过程简单,处理成本低,适合于大批量的工业化生产,有望成为制备高稳定性微电子器件与电路系统的必需工艺技术.     

安全门系统地铁通风空调能耗模拟分析

以南京地铁1号线通风空调系统为研究对象,采用三维模型和网络模型求解相结合的方法.并通过数值模拟技术对地铁车站安装安全门系统前后通风空调能耗的变化进行了研究.结果认为,南京地区地铁采用安全门系统能起到降低通风空调能耗的作用,安全门越高,即门上方孔隙越小,能耗越低,但总降幅不超过15%.     

Dry phosphorus silicate glass etching for multicrystalline silicon solar cells

A dry plasma etching process for phosphorus silicate glass (PSG) in a SiN‐PECVD batch reactor is developed. In the same reactor PSG etching and anti‐reflective coating (ARC) can be performed successively. To demonstrate industrial feasibility, screen‐printed solar cells are manufactured and compared with cells prepared by a standard wet chemical process. Copyright © 2003 John Wiley & Sons, Ltd.