Clinical significance of contact lens related changes of ocular surface tissue observed on optical coherence images

PurposeTo investigate the relationship between the real contact lens imprint into the conjunctival tissue, observed by optical coherence tomography (OCT) and conjunctival staining and contact lens wearing comfort.Methods17 participants (mean age = 26.6 SD ± 3.6 years; 7 females) were fitted with three different contact lenses base curves of the same silicone hydrogel custom lens type (Visell 50; Hecht Contactlinsen, Au, Germany) in a randomised order. One lens was optimally fitted according to the manufacturer's recommendation, one fitted 0.4 mm flatter and one fitted 0.4 mm steeper. After 4 h of lens wear the contact lens edge in the area of the conjunctiva was imaged nasally and temporally using OCT (Optovue iVue SD-OCT). To correct the artefact due to optical distortion with OCT, the imprint of all worn lenses was measured on a glass plate afterwards. Conjunctival staining in the limbal region after 4 h of lens wear was classified using the CCLRU Grading Scale. Comfort scoring was based on visual analog scales from 0 (very poor) to 100 (excellent).ResultsThe mean conjunctival imprint of all contact lens edges was 32.0 ± 8.1 μm before and 7.3 ± 6.5 μm after distortion correction of the OCT images. The distortion corrected conjunctival imprint with the 0.4 mm steeper lens (11.5 ± 6.2 μm) was statistically significantly greater compared to the optimally fitted lens (6.5 ± 5.9 μm) (One-way ANOVA followed Tukey-test; p = 0.017) and greater compared to the 0.4 mm flatter lens (3.9 ± 5.3 μm) (p < 0.001). There was no statistically significant difference between the optimally fitted lens and the 0.4 mm flatter lens (p = 0.209). The nasally measured imprint (11.4 ± 9.0 μm) was significantly greater than the temporally measured (3.3 ± 7.6 μm) (p < 0.001). There was no statistically significant correlation between the amount of conjunctival imprint and the graded conjunctival staining (p = 0.346) or the wearer’s comfort (p = 0.735).ConclusionsContact lens edges imaged by OCT exhibited displacement artefacts. The observed conjunctival imprints are a combination of real conjunctival compression and artefacts. A deeper imprint of the contact lens into the conjunctiva caused by a steeper base curve was not related to clinically significant staining or changes in comfort after 4 h of lens wear. The observed differences between nasal and temporal imprint are likely to be caused by variations of conjunctival thickness and the shape of the underlying sclera.     

连续波半主动雷达制导空空导弹截获跟踪距离计算

分析了连续波半主动雷达制导导弹导引头工作电磁环境和对武器系统攻击区的影响，建立了热噪声和杂波干扰环境下导引头截获距离方程，分析推导了直波泄漏干扰，地杂波干扰的计算公式，并在此基础上给出了导弹允许攻击区计算公式。     

一种PD雷达动目标模拟与微波测控系统

介绍了一种基于PC／104总线，具有GPIB程控功能，采用无内部微波源体制，通过在雷达载频上调制多普勒频率模型目标速度信息，延迟雷达发射机触发脉冲模拟目标距离信息并具有微波功率精确定标与衰减功能的PD雷达动目标模拟与微波测控系统。     

OCT图像散斑的形成机理和清除方法

根据光相干层析成像（OCT）的光学和光电检测系统特点，结合现有的理论模型，分析了OCT成像和散斑形成机理。指出失去相干性的多次散射光部分会被滤波电路排除，散斑是由高散射组织相干长度之内的不同散射截面上的若干具有nπ光程差的相干散射光彼此叠加形成的。最后讨论了消除散斑的方法。     

用于提高国产氩离子激光器相干长度的相干扩展器

本文报导了最近研制成功的用于提高国产氩离子激光器相干长度的相干扩展器。利用这种基于F-P理论的相干扩展器可以使国产氩离子激光器的相干长度由不足5cm一下提高到m的量级,功率损耗在25%～40%之间,有着很好的应用前景。     

瑞利与非瑞利杂波背景下单、双参数杂波图的性能分析

对瑞利和非瑞利杂波中的单、双参数杂波图的控制虚警性能和检测性能进行了比较分析，并得到了双参数杂波图门限调整值的取值范围，得出了几点有益的结论。     

相控阵AEW雷达杂波抑制的辅助通道方法研究

本文分析了相控阵机载预警(AEW)雷达杂波抑制的现有两种辅助通道降维技术(Klemm方法和简化方法)的性能，并提出了一种新的辅助通道方法。新方法的基本思想为：根据待处理距离段内各距离单元杂波能量在波束一多普勒域分布的统计特征自适应地选取辅助通道，使所选辅助通道实时地逼近杂波子空间，从而有效抑制杂波。本文方法不但可以用于非正侧视阵情况，而且误差鲁棒性好。计算机仿真结果证实了其有效性。     

GH2027铁基高温合金的第二相研究

运用电子显微分析和波谱分析等方法对ＧＨ２０２７合金的第二相进行了研究，结果表明，合金晶界相主要是片状Ｍ６Ｃ和薄膜状Ｍ２３Ｃ６，经波纹图样测得其错配度约为３％，晶内Ｍ６Ｃ和Ｍ２３     

裂缝性潜山储层地震描述技术

裂缝是潜山油气藏的重要储集层 ,潜山的油气产出与裂缝的发育情况密切相关 ,因此 ,对裂缝发育控制因素和裂缝发育规律进行了分析和探讨。尽管单条裂缝在地震资料上难以识别 ,但是裂缝带在地震资料上有其特征。描述了裂缝储层的地球物理特征 ,并利用测井约束反演技术、吸收系数技术、地震相分类和相干分析技术对潜山储层进行预测。通过在车古 2 0 1潜山的应用实例分析 ,说明以上 4种储层描述技术比较有效     

雷达仿真系统中电磁干扰环境的仿真设计和实施

雷达仿真系统是为检测雷达设备的抗干扰能力以及在各种电磁环境下的工作性能而设计的，包括有源干扰和无源干扰的模拟仿真。本文阐述了无源干扰即杂波的散射模型和仿真过程；从同步脉冲干扰的基本原理出发，阐明在雷达工作环境仿真系统中距离拖引、速度拖引、虚假目标等同步脉冲有源干扰的设计和实施过程；并针对工作在搜索和跟踪交替模式下的相控阵雷达提出自适应综合干扰方式；最后分析并总结了系统仿真时为真实、有效地模拟电磁干扰环境应注意的关键问题。