Author Keywords: Radiation detection; Long-lasting phosphor; Luminescence; Temperature dependence; Fade-out effect 相似文献
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1.
Amphetamine and cocaine dependence present significant public health concerns, yet no broadly effective pharmacotherapy for stimulant dependence has been developed. Two human laboratory studies are reviewed that tested the ability of aripiprazole, a novel antipsychotic with partial agonist activity at D2 dopamine receptors, to alter the behavioral effects of stimulants using d-amphetamine as a model agent. In each of these experiments, volunteers learned to discriminate 15 mg d-amphetamine (i.e., ≥80% drug-appropriate responding over 4 consecutive sessions). The effects of a range of doses of d-amphetamine (0, 2.5, 5, 10, and 15 mg) were then tested alone and following pretreatment with aripiprazole (20 mg in Experiment 1; 10 mg in Experiment 2). In Experiment 1, aripiprazole (20 mg) attenuated the discriminative stimulus and many of the subject-rated effects of amphetamine. Aripiprazole alone produced performance decrements. To determine whether a lower dose of aripiprazole would also attenuate the behavioral effects of d-amphetamine without impairing performance, Experiment 2 was conducted. Aripiprazole (10 mg) failed to alter the discriminative-stimulus effects but attenuated some of the subject-rated effects of d-amphetamine. This dose of aripiprazole did not impair performance. The results of these experiments indicate that aripiprazole may have clinical utility in treating stimulant dependence. Future human laboratory research should better model the clinical use of aripiprazole by examining the effects of chronic aripiprazole combined with either methamphetamine or cocaine in dependent individuals. A large-scale clinical trial is also needed to evaluate the efficacy of aripiprazole for the treatment of stimulant dependence. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
2.
S.J. Curran R.E. Hayes A. Afacan M.C. Williams P.A. Tanguy 《Journal of food science》2002,67(1):176-180
ABSTRACT: The effect of pH on the non-Newtonian viscosity (η)of aqueous Carbopol 940 solutions is presented with high resolution (pH increments about 0.4) between pH = 2.8 and 12.7. Aqueous NaOH was used to adjust pH of 1.48 wt % Carbopol solutions. A Contraves viscometer was used to measure steady-flow shear stress at known shear rate (γ) over the range γ= 8 to 195 s−1 . Yield stresses and shear-thinning η(γ) were observed. Data were fitted with a Herschel-Bulkley model, whose parameters (including yield stress) were expressed as functions of pH. Comparisons were made of η(γ) to the dynamic viscometric properties η'(ω) and η*(ω) for comparable ranges of γ and frequency (ω): A fairly close match was found between η and η* but η«η'. pH dependence included previously unreported extrema of h(pH) in the range of pH = 6.2 to 6.6. Because of sensitive control of rheological properties with pH, Carbopol solutions can be used to mimic a great range of shear-thinning and yield-stress behavior that should make them useful for model studies directed toward process and equipment design and evaluation. 相似文献
3.
Lash Steven J.; Stephens Robert S.; Burden Jennifer L.; Grambow Steven C.; DeMarce Josephine M.; Jones Mark E.; Lozano Brian E.; Jeffreys Amy S.; Fearer Stephanie A.; Horner Ronnie D. 《Canadian Metallurgical Quarterly》2007,21(3):387
Although continuing care is strongly related to positive treatment outcomes for substance use disorder (SUD), participation rates are low and few effective interventions are available. In a randomized clinical trial with 150 participants (97% men), 75 graduates of a residential Veterans Affairs Medical Center SUD program who received an aftercare contract, attendance prompts, and reinforcers (CPR) were compared to 75 graduates who received standard treatment (STX). Among CPR participants, 55% completed at least 3 months of aftercare, compared to 36% in STX. Similarly, CPR participants remained in treatment longer than those in STX (5.5 vs. 4.4 months). Additionally, CPR participants were more likely to be abstinent compared to STX (57% vs. 37%) after 1 year. The CPR intervention offers a practical means to improve adherence among individuals in SUD treatment. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
4.
Munehiko Kowatari Daisuke Koyama Yoshiyuki Satoh Kouichi Iinuma Shunsuke Uchida 《Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment》2002,480(2-3):431-439
The temperature dependence of luminescence from a long-lasting phosphor (LLP), SrAl2O4 : Eu2+,Dy3+, exposed to ionizing radiation has been measured to understand the LLP luminescence mechanism. Evaluation of the decay constants of the LLP exposed to -, β- or γ-rays at temperatures from 200 to 390 K showed that the decay constant is divided into four components ranging from 10−4 to 10−1 s−1 with activation energies of 0.02–0.35 eV.
Total luminous intensity from the LLP with changing irradiation temperature has its maximum value around the room temperature. Irradiation at elevated temperature (390 K) has the total luminescence pattern with monotonous decrease as temperature rises. As a result of evaluating the temperature dependence of luminescence, the luminescence mechanism is considered as follows:
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不良的生活方式和个人行为对健康是一种“自我制造的危害”。吸烟有害世人皆知,然而,近年来吸烟大军更表现为年青化、女性化的特点,青年大学生们吸烟也较普遍,烟草危害在吸烟者身上表现也很明显,已给国家造成极大的疾病负担;青年大学生吸烟还有漫延之势,必须积极开设健康教育,传授保健知识,让他们自己起来同不良的生活习惯作斗争,同时,还必须制定有效的行政干预措施,才能把吸烟带来的毒害控制在最小范围。 相似文献
7.
Reviews the book, The chemically dependent: Phases of treatment and recovery edited by Barbara C. Wallace (see record 1992-98403-000). While this book is ambitious, interesting, educational, and useful, it is also disappointing, repetitious, and incomplete. Because it tries to accomplish so much, it may appear to have succeeded too little. This book is organized around, and explicative of, several basic ideas which might have been controversial if not heretical had this book been published ten years ago. Section I, purporting to link specific "phases of recovery" to particular forms and functions of treatment, will certainly be useful for novice clinicians but falls short of its overstated goals and is thereby disappointing. Section II is a collection of moderately redundant chapters describing the etiology and treatment of substance abusers from the viewpoints of psychoanalytic, psychodynamic, ego psychology, and object-relations theorists and therapists. Section III focuses on cognitive-behavioral, self-help, and relapse-prevention treatments. Section IV is quite uneven in quality of writing and applicability of content, and could have benefited from closer editorial scrutiny or selectivity. The final section focuses on special needs of particular subpopulations of substance abusers: African-Americans, prison inmates, HIV/AIDS patients, persons who are homeless, those who have been sexually and physically abused, and others. According to the reviewer this is not the best book on substance abuse treatment, but it does present some clinically useful ideas and it is worth reading. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
8.
Plasmapropertiesoflaser-ablatedSttargetinairWangXiang-Tai(王象泰);ManBao-Yuan(满宝元);WangGong-Tang(王公堂);FanXi-Jun(樊锡君);WangJun(王军)... 相似文献
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10.
We propose an approach for dependence tree structure learning via copula. A nonparametric algorithm for copula estimation is presented. Then a Chow-Liu like method based on dependence measure via copula is proposed to estimate maximum spanning bivariate copula associated with bivariate dependence relations. The main advantage of the approach is that learning with empirical copula focuses on dependence relations among random variables, without the need to know the properties of individual variables as well as without the requirement to specify parametric family of entire underlying distribution for individual variables. Experiments on two real-application data sets show the effectiveness of the proposed method. 相似文献