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排序方式: 共有415条查询结果,搜索用时 31 毫秒
1.
《Contact lens & anterior eye》2021,44(6):101388
PurposeTo investigate the relationship between the real contact lens imprint into the conjunctival tissue, observed by optical coherence tomography (OCT) and conjunctival staining and contact lens wearing comfort.Methods17 participants (mean age = 26.6 SD ± 3.6 years; 7 females) were fitted with three different contact lenses base curves of the same silicone hydrogel custom lens type (Visell 50; Hecht Contactlinsen, Au, Germany) in a randomised order. One lens was optimally fitted according to the manufacturer's recommendation, one fitted 0.4 mm flatter and one fitted 0.4 mm steeper. After 4 h of lens wear the contact lens edge in the area of the conjunctiva was imaged nasally and temporally using OCT (Optovue iVue SD-OCT). To correct the artefact due to optical distortion with OCT, the imprint of all worn lenses was measured on a glass plate afterwards. Conjunctival staining in the limbal region after 4 h of lens wear was classified using the CCLRU Grading Scale. Comfort scoring was based on visual analog scales from 0 (very poor) to 100 (excellent).ResultsThe mean conjunctival imprint of all contact lens edges was 32.0 ± 8.1 μm before and 7.3 ± 6.5 μm after distortion correction of the OCT images. The distortion corrected conjunctival imprint with the 0.4 mm steeper lens (11.5 ± 6.2 μm) was statistically significantly greater compared to the optimally fitted lens (6.5 ± 5.9 μm) (One-way ANOVA followed Tukey-test; p = 0.017) and greater compared to the 0.4 mm flatter lens (3.9 ± 5.3 μm) (p < 0.001). There was no statistically significant difference between the optimally fitted lens and the 0.4 mm flatter lens (p = 0.209). The nasally measured imprint (11.4 ± 9.0 μm) was significantly greater than the temporally measured (3.3 ± 7.6 μm) (p < 0.001). There was no statistically significant correlation between the amount of conjunctival imprint and the graded conjunctival staining (p = 0.346) or the wearer’s comfort (p = 0.735).ConclusionsContact lens edges imaged by OCT exhibited displacement artefacts. The observed conjunctival imprints are a combination of real conjunctival compression and artefacts. A deeper imprint of the contact lens into the conjunctiva caused by a steeper base curve was not related to clinically significant staining or changes in comfort after 4 h of lens wear. The observed differences between nasal and temporal imprint are likely to be caused by variations of conjunctival thickness and the shape of the underlying sclera. 相似文献
2.
Critical-point drying and freeze drying were compared both quantitatively and qualitatively as preparative procedures for scanning electron microscopy. Isolated hepatocytes were used as model cells. Nomarski differential interference contrast microscopy was used for light microscopic measurements of the hepatocytes in the unfixed, the glutaraldehyde fixed, the glutaraldehyde + OsO4 fixed, the critical-point dried and the freeze dried states. Critical-point dried hepatocytes were found to shrink to 38% of glutaraldehyde + OsO4 fixed volume, whereas optimal freeze dried hepatocytes (frozen in water saturated with chloroform and freeze dried at 183 K for 84 h) were found to shrink to 51% of glutaraldehyde + OsO4 fixed volume. Transmission and scanning electron micrographs of the critical-point dried cells showed well-preserved ultrastructure and surface structure. Micrographs of the freeze dried cells showed ultrastructure destroyed by internal ice crystals and surface structure destroyed by external ice crystals. Double-fixed isolated hepatocytes were shown to swell during storage in buffer and to shrink during storage after critical-point drying. For low magnification scanning electron microscopy (up to about 3000 times) both critical-point drying and freeze drying can be used. However, for high magnification scanning electron microscopy, critical-point drying is superior to freeze drying. 相似文献
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4.
Simonetta Balsamo Vittoria De Nitto Person Paola Inverardi 《Performance Evaluation》2003,51(2-4):269-288
A review is carried out on how queueing network models with blocking have been applied so far into the performance evaluation and prediction of Software Architectures (SA). Queueing network models with finite capacity queues and blocking have recently been introduced and applied as more realistic models of systems with finite capacity resources and population constraints. Queueing network models have been often adopted as models for the evaluation of software performance. Starting from our own experience, we observe the need of a more accurate definition of the performance models of SA to capture some features of the communication systems. We consider queueing networks with finite capacity and blocking after service (BAS) to represent some synchronization constraints that cannot be easily modeled with queueing network models with infinite capacity queues. We investigate the use of queueing networks with blocking as performance models of SA with concurrent components and synchronous communication. Queueing theoretic analysis is used to solve the queueing network model and study the synchronous communication and performance of concurrent software components. Our experience is supported by other approaches that also propose the use of queueing networks with blocking. Directions for future research work in the field are included. 相似文献
5.
Emergency department status boards: user-evolved artefacts for inter- and intra-group coordination 总被引:1,自引:1,他引:0
Robert L. Wears Shawna J. Perry Stephanie Wilson Julia Galliers James Fone 《Cognition, Technology & Work》2007,9(3):163-170
Large, easily viewed status boards are commonly used in some healthcare settings such as emergency departments, operating
theaters, intensive care units, and inpatient wards. Because these artefacts were developed by front-line users, and have
little to no supervisory or regulatory control, they offer valuable insights into the theories of work and hazard held by
those users. Although the status boards case were locally developed over many years for within-group coordination, they have
also become useful for between-group coordination across organizational boundaries. In this paper, we compare and contrast
the use of such status boards in two disparate settings: a US emergency department, and a UK pediatric ward, and note striking
similarities in their form and usage, despite the large differences in setting. 相似文献
6.
7.
Xiangqing Tian Xiaoqiong Qi Qiongfang Ma Xiaoping Zhang 《Photonic Network Communications》2006,11(3):271-276
A new design scheme for a distributed algorithm for routing and wavelength assignment (RWA) is developed in this paper, and
the communication rules between the nodes to exchange signaling packets are discussed. The Adaptive-Alternate-Routing-Least-Load
(AARLL) algorithm is implemented in the distributed scheme for the first time. Under dynamic traffic circumstances, the influence
of the race condition, which does not exist in centralized scheme, on the network performance is analyzed and the analyzed
results show that the race condition has a major impact on network performance only under light traffic load, while under
medium and heavy traffic load the impact is very small. To analyze the performance loss caused by adopting the distributed
algorithm for RWA, the capacity loss factor (CLF) is introduced and the calculated results show that CLF does not exceed 6%
under medium traffic load. 相似文献
8.
1998年九江抗洪启示录 总被引:2,自引:0,他引:2
简述1998年江西特大洪水的基本情况,重点介绍了九江防洪的形势和九江长江城防堤4~5号闸口间堤段溃决的情况及堵口过程,并总结了经验教训和抗洪工作的体会. 相似文献
9.
10.
Upon the application of amperometric biosensor to the biological fluid, ascorbic acid interferes the amperometric determination of analytes, because the oxidative potential of ascorbic acid is lower than that of electro active substances such as H2O2 produced by the enzymatic reaction. In this study we propose a method to block ascorbic acid based on the electrostatic interaction with self-assembled monolayer (SAM) and its application of the surface modified electrode to biosensor. In order to form SAM on the gold electrode with carboxyl group, 7-carboxy-heptanethiol (7-CHT) was used. The 7-CHT modified electrode did not show anodic response to ascorbic acid, but oxidized phenanthroline cobalt complex [Co(phen)32+], which can be used as a mediator of biosensor. Thus, the 7CHT-modified electrode was applied to biosensor mediated with Co(phen)32+. Fructose dehydrogenase (FDH) was immobilized to the 7-CHT modified electrode. Fructose was determined selectively with the FDH/7-CHT modified electrode at the range of 0.2-2 mM. 相似文献