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1.
The rate of penetration (ROP) model is of great importance in achieving a high efficiency in the complex geological drilling process. In this paper, a novel two-level intelligent modeling method is proposed for the ROP considering the drilling characteristics of data incompleteness, couplings, and strong nonlinearities. Firstly, a piecewise cubic Hermite interpolation method is introduced to complete the lost drilling data. Then, a formation drillability (FD) fusion submodel is established by using Nadaboost extreme learning machine (Nadaboost-ELM) algorithm, and the mutual information method is used to obtain the parameters, strongly correlated with the ROP. Finally, a ROP submodel is established by a neural network with radial basis function optimized by the improved particle swarm optimization (RBFNN-IPSO). This two-level ROP model is applied to a real drilling process and the proposed method shows the best performance in ROP prediction as compared with conventional methods. The proposed ROP model provides the basis for intelligent optimization and control in the complex geological drilling process.  相似文献   
2.
Multicellular tumor spheroid models (MCTS) are often coined as 3D in vitro models that can mimic the microenvironment of tissues. MCTS have gained increasing interest in the nano‐biotechnology field as they can provide easily accessible information on the performance of nanoparticles without using animal models. Considering that many countries have put restrictions on animals testing, which will only tighten in the future as seen by the recent developments in the Netherlands, 3D models will become an even more valuable tool. Here, an overview on MCTS is provided, focusing on their use in cancer research as most nanoparticles are tested in MCTS for treatment of primary tumors. Thereafter, various types of nanoparticles—from self‐assembled block copolymers to inorganic nanoparticles, are discussed. A range of physicochemical parameters including the size, shape, surface chemistry, ligands attachment, stability, and stiffness are found to influence nanoparticles in MCTS. Some of these studies are complemented by animal studies confirming that lessons from MCTS can in part predict the behaviour in vivo. In summary, MCTS are suitable models to gain additional information on nanoparticles. While not being able to replace in vivo studies, they can bridge the gap between traditional 2D in vitro studies and in vivo models.  相似文献   
3.
纤维在沥青混合料中的应用研究   总被引:1,自引:0,他引:1  
张争奇  陶晶 《石油沥青》2006,20(5):26-32
选用工程中常用的几种纤维,结合工程应用要求,试验分析了纤维的吸湿性、耐热性,并通过网篮析漏试验、动态剪切试验和沉锥试验,讨论了纤维对沥青的稳定和吸附作用,以及纤维对沥青混合料“加筋”效果和作用机理。研究表明有的纤维“吸附、稳定”性能好,而有的纤维“加筋、桥接”效果好,在应用纤维时,应根据纤维的主要特点以及沥青混合料的使用要求来选用。  相似文献   
4.
The effects of the cuticle and epicuticular waxes of grapefruit, strawberry and apple on the photodegradation and penetration of chlorpyrifos-methyl were studied. Photodegradation experiments were conducted by exposing the insecticide to the light of a xenon lamp in the presence of a film of wax extracted from the fruit surface. The half-life of chlorpyrifos-methyl irradiated in absence of waxes was 9.6 min. The half-lives of pesticide irradiated in the presence of wax extracts of apple, grapefruit and strawberry were 83, 34 and 26 min, respectively. In penetration studies, fruit with and without wax layers were treated with an aqueous suspension of pesticide. The penetration of the pesticide from the cuticle to the pulp was measured after 24 h. Samples without wax contained a higher total amount of insecticide than those with wax. No pesticide was detected in samples of apple and grapefruit pulp. Residues were detected in all fractions of strawberry. The waxes and cuticle appear to have some effect on the photodegradation and penetration of chlorpyrifos-methyl in fruit samples.  相似文献   
5.
影视后期制作或图像合成中,动态实时改变显示画面的景深能进一步增强画面的真实感,但由于实时性要求较高,软件实现在处理速度方面容易产生瓶颈。为此,采用预处理的办法,分别对前景和背景进行低通滤波,得到前、背景各自的模拟帧序列,通过调节前景和背景帧序列的位置,模拟确定其各自的变焦程度,然后将前景和背景动态合成具有虚拟景深效果的画面。  相似文献   
6.
涡轮钻具在高陡构造的应用及展望   总被引:1,自引:1,他引:0  
介绍了涡轮钻具在秋参1井的应用情况,详细叙述了涡轮钻具在山前高陡构造快速钻进及防斜打直方面的优点,与常规钻井相比,机械钻速明显提高,钻井周期明显缩短,钻井成本明显下降,经济效益显著。  相似文献   
7.
深穿透复合射孔技术在中原油田的应用   总被引:1,自引:0,他引:1  
深穿透复合射孔是一项把射孔与高能气体压裂两种技术有机地结合在一起的综合改造油气层的新技术。重点对它的技术原理,包括设计原理、枪身内火药燃烧气体对射孔孔眼的冲刷作用原理、火药燃烧气体射流的高能气体压裂作用原理等进行了研究与探讨,同时对它的施工工艺、现场应用等方面进行了阐述,经中原油田189口井现场应用证明,其工艺简便,成本低廉,可实现多层跨隔层使用,处理后增产效果显著,投入产出比高,可代替传统的聚能射孔技术,具有广阔的推广和应用价值。  相似文献   
8.
A theory is presented that explains how the visual system infers the lightness, opacity, and depth of surfaces from stereoscopic images. It is shown that the polarity and magnitude of image contrast play distinct roles in surface perception, which can be captured by 2 principles of perceptual inference. First, a contrast depth asymmetry principle articulates how the visual system computes the ordinal depth and lightness relationships from the polarity of local, binocularly matched image contrast. Second, a global transmittance anchoring principle expresses how variations in contrast magnitudes are used to infer the presence of transparent surfaces. It is argued that these principles provide a unified explanation of how the visual system computes the 3-D surface structure of opaque and transparent surfaces. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
9.
地震勘探技术应用可以分为以二维地震研究构造为主的地震勘探初级阶段、以地震地层学为主的地震勘探中级阶段、以三维地震油藏静态描述为主的地震勘探高级阶段、以地震储层研究为主的开发地震妆级阶段和以四维地震进行油藏监测为主的开发地震高级阶段。针对5个不同阶段的地质条件和地质任务,选择使用合理的地震勘探技术是有效提高勘探开发效益的重要途径。焉耆盆地的勘探开发体现了以地震勘探为主的思路,在勘探开发过程中重视了针对不同勘探开发阶段和不同的地质 地震技术,因此,在早期勘探开发中取得了很好的经济效益。  相似文献   
10.
A long thin conducting stripline embedded in a dielectric and centered between two large conducting plates, i.e., the stripline environment, is considered. The stripline is modeled as infinitely long, infinitely thin, and perfectly conducting by first considering a stripline of finite length, thickness, and conductivity in a dielectric layer. Starting from Maxwell's equations and assuming that the current on the stripline is a propagating wave in length direction, asymptotic expressions for the fields inside and in the neighbourhood of the stripline are deduced. These expressions are used to model the stripline in the stripline environment, which leads to a boundary-value problem for the electric potential. This problem is solved by two different approaches, leading to integral equations for the current and for an auxiliary function describing the electric potential. A relation between the current and the auxiliary function is deduced, which is used to obtain asymptotic expressions for current and impedance. Results are compared with a numerical solution of the integral equation for the current and with results in literature.  相似文献   
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