Realization of a self-recognition algorithm based on the biological immune system

As the use of the computer is popularized, the damage from computer viruses and hacking by malicious users is increasing rapidly. To block the hacking that is an intrusion into a person's computer, and the viruses that destroy data, a study into an intrusion detection and virus detection system based on the biological immune system is in progress. In this article, we describe a model of positive and negative selection for self-recognition, which has a similar function to the cytotoxic T cells that play an important role in the biological immune system. We propose a self/nonself discrimination algorithm for a computer system, which will the important when we detect data infected by a computer virus, of data modified by an intrusion from outside. We also show the validity and effectiveness of the proposed self-recognition algorithm by a computer simulation of some infected data obtained from cell changes and string changes in the self-file. This work was presented, in part, at the Seventh International Symposium on Artificial Life and Robotics, Oita, Japan, January 16–18, 2002     

MHC合金粉末冶金制备及其锻造棒材力学性能研究

针对MHC合金粉末的冶金制备工艺及其烧结坯性能、锻造态和经热处理后的MHC合金棒组织与力学性能开展研究。结果表明:所研究的粉末冶金工艺参数可制备出适宜于锻造加工的MHC烧结棒坯;相比于烧结坯,经88.6%锻造比锻造后MHC合金棒材的硬度、强度显著提高;经88.6%锻造比锻造后的MHC合金棒材的完全再结晶温度高于1500℃,经1200℃保温1 h热处理后,MHC合金棒材的室温强度Rp 0.2>770 MPa,硬度达到HRA 66.5;真空气氛下800℃高温拉伸强度Rp 0.2>450 MPa,延伸率大于18.5%。表明本研究制备的MHC合金棒材具备显著的室温高强高硬特性和良好的高温综合力学性能。     

Embedding in Spurr's resin is a good choice for immunolabelling after freeze drying as shown with chemically unfixed dendritic cells

Immunocytochemical reactions on biological specimens depend on many factors, the most crucial one being the maintenance of antigenicity. Antigens are vulnerable at each stage during preparation for electron microscopy. One of the least traumatic methods of preparing biological tissues for post‐embedding immunolabelling includes the following steps: (1) physical stabilization of the native biological material by rapid freezing (cryofixation) and keeping the immobilized biological sample at low temperature, thereby avoiding any movements of water, ions and macromolecules; (2) dehydrating the frozen biological material by freeze‐drying at low temperature; (3) embedding of the dehydrated specimen. Here we show that embedding of chemically unfixed dendritic cells in Spurr's resin after cryofixation and freeze‐drying enables the conservation of fine ultrastructure without cell distortion or shrinkage. Furthermore, we demonstrate the feasibility of protein localization in ultrathin sections by immunolabelling of the major histocompatibility class II molecules.     

纳秒脉冲触发的阵列微空心阴极放电特性

阵列微空心阴极(MHC)是一种在同一个阴极结构上加工多个微孔形成微孔阵列,实现大面积高电子密度的放电微等离子体结构。相比直流触发模式,纳秒短脉冲触发阵列微空心阴极,可以显著地减少直流触发时的电流热负荷效应,提高放电电流和放电能量。本文利用自行研制的纳秒脉冲电源,实现对阵列微空心阴极在氩气下进行脉冲放电,研究其脉冲条件下的放电特性;其次,研究其在纳秒脉冲下多孔阵列的同步放电问题,并通过加入预触发结构,有效改善其同步特性;最后,利用光纤式发射光谱仪进行氩气下氩发射光谱测量,并对纳秒放电等离子体进行光谱诊断。