OCT图像散斑的形成机理和清除方法

根据光相干层析成像（OCT）的光学和光电检测系统特点，结合现有的理论模型，分析了OCT成像和散斑形成机理。指出失去相干性的多次散射光部分会被滤波电路排除，散斑是由高散射组织相干长度之内的不同散射截面上的若干具有nπ光程差的相干散射光彼此叠加形成的。最后讨论了消除散斑的方法。     

具有未知时滞的线性连续系统的辨识

本文给出了一种频域方法,它能用来辨识具有未知时滞的连续过程.     

基于电容电流的谐波电压在线监测系统研制

我国变电站内的谐波电压监测数据大多取自电容式电压互感器（CVT）的测量结果,受CVT本身工频谐振设计的影响,谐波电压测量数据存在较大畸变。在国家电网公司推广建设电能质量监测平台背景下,针对国内市场上测量准确且简便易行的CVT谐波电压在线监测装置的空白,研制一套基于电容电流法的CVT谐波电压在线监测系统,纠正现场普遍存在的CVT谐波电压测量结果畸变;同时,通过对不同谐波电压测量方法的分析和试验对比,为在不同现场选取适合的谐波电压测量方法提供参考依据。该系统施工量小、准确度高、适用面广,具有良好的工程应用价值。     

三维声纳频域波束形成算法的优化及实现

为了对三维声纳频域波束形成算法进行优化,提出了一种算法的优化方法。利用声纳回波信号的位移矢量分解与合成原理,推导出波束强度与相应方向角的数学关系式,进而使算法得到优化,并对优化的波束形成算法进行了仿真。同时,给出了实现此算法的两种数据通路,并对其内存需求量和计算量进行了分析。最终在XilinxISE环境下,在现场实现可编程门阵列(FPGA)上对该两种数据通路进行了仿真,并列出了相应的资源利用情况。优化后的算法不仅可以得到与传统算法相同的波束强度矩阵结果,而且减少了存储相移参数所需的内存空间。     

An Ophthalmic Evaluation of Central Serous Chorioretinopathy

Nowadays in the medical field, imaging techniques such as Optical Coherence Tomography (OCT) are mainly used to identify retinal diseases. In this paper, the Central Serous Chorio Retinopathy (CSCR) image is analyzed for various stages and then compares the difference between CSCR before as well as after treatment using different application methods. The first approach, which was focused on image quality, improves medical image accuracy. An enhancement algorithm was implemented to improve the OCT image contrast and denoise purpose called Boosted Anisotropic Diffusion with an Unsharp Masking Filter (BADWUMF). The classifier used here is to figure out whether the OCT image is a CSCR case or not. 150 images are checked for this research work (75 abnormal from Optical Coherence Tomography Image Retinal Database, in-house clinical database, and 75 normal images). This article explicitly decides that the approaches suggested aid the ophthalmologist with the precise retinal analysis and hence the risk factors to be minimized. The total precision is 90 percent obtained from the Two Class Support Vector Machine (TCSVM) classifier and 93.3 percent is obtained from Shallow Neural Network with the Powell-Beale (SNNWPB) classifier using the MATLAB 2019a program.     

全分布式光纤温度传感器研究的进展及趋势

综述了基于光时域反射和光频域反射的分布式温度光纤传感器的原理、技术以及最新的研究进展 ,并在此基础上分析了温度光纤传感器的发展趋势。     

Research on the improved frequency-domain equalization algorithm for OFDM underwater acoustic communication

The traditional OFDM frequency-domain equalization algorithm depends on the long circular prefix to overcome the bad influences caused by multi-path effects in the underwater acoustic channel. But the redundant long prefix is actually a serious waste of energy and bandwidth in underwater systems, which restrains the OFDM signal's advantages of high channel utilization greatly. Aiming at the defects of the traditional equalization algorithm, this paper brings forward a new frequency-domain equalization algorithm based on the analysis of the influences caused by multi-path effects and the equalization theory and structure. The results of simulation show that the new algorithm can compensate the multi-path effects efficiently with few circular prefixes and make sure the high-speed and reliability of the underwater acoustic communication system. Finally, based on the amount of computing, a simple algorithm is given.     

Stationary and Progressive Phenotypes Caused by the p.G90D Mutation in Rhodopsin Gene

Mutations in rhodopsin gene (RHO) are a frequent cause of retinitis pigmentosa (RP) and less often, congenital stationary night blindness (CSNB). Mutation p.G90D has previously been associated with CSNB based on the examination of one family. This study screened 60 patients. Out of these 60 patients, 32 were affected and a full characterization was conducted in 15 patients. We described the clinical characteristics of these 15 patients (12 male, median age 42 years, range 8–71) from three families including visual field (Campus Goldmann), fundus autofluorescence (FAF), optical coherence tomography (OCT) and electrophysiology. Phenotypes were classified into four categories: CSNB (N = 3, 20%) sector RP (N = 3, 20%), pericentral RP (N = 1, 6.7%) and classic RP (N = 8, 53.3% (8/15)). The phenotypes were not associated with family, sex or age (Kruskal–Wallis, p > 0.05), however, cystoid macular edema (CME) was observed only in one family. Among the subjects reporting nyctalopia, 69% (22/32) were male. The clinical characteristics of the largest p.G90D cohort so far showed a large frequency of progressive retinal degeneration with 53.3% developing RP, contrary to the previous report.     

Robust eigenstructure clustering by non-smooth optimisation

We extend classical eigenstructure assignment to more realistic problems, where additional performance and robustness specifications arise. Our aim is to combine time-domain constraints, as reflected by pole location and eigenvector structure, with frequency-domain objectives such as the H₂, H_∞ or Hankel norms. Using pole clustering, we allow poles to move in polydisks of prescribed size around their nominal values, driven by optimisation. Eigenelements, that is poles and eigenvectors, are allowed to move simultaneously and serve as decision variables in a specialised non-smooth optimisation technique. Two aerospace applications illustrate the power of the new method.     

Molecular Contrast Optical Coherence Tomography and Its Applications in Medicine

The growing need to understand the molecular mechanisms of diseases has prompted the revolution in molecular imaging techniques along with nanomedicine development. Conventional optical coherence tomography (OCT) is a low-cost in vivo imaging modality that provides unique high spatial and temporal resolution anatomic images but little molecular information. However, given the widespread adoption of OCT in research and clinical practice, its robust molecular imaging extensions are strongly desired to combine with anatomical images. A range of relevant approaches has been reported already. In this article, we review the recent advances of molecular contrast OCT imaging techniques, the corresponding contrast agents, especially the nanoparticle-based ones, and their applications. We also summarize the properties, design criteria, merit, and demerit of those contrast agents. In the end, the prospects and challenges for further research and development in this field are outlined.