What Can We Learn from FGF-2 Isoform-Specific Mouse Mutants? Differential Insights into FGF-2 Physiology In Vivo

Fibroblast growth factor 2 (FGF-2), ubiquitously expressed in humans and mice, is functionally involved in cell growth, migration and maturation in vitro and in vivo. Based on the same mRNA, an 18-kilo Dalton (kDa) FGF-2 isoform named FGF-2 low molecular weight (FGF-2LMW) isoform is translated in humans and rodents. Additionally, two larger isoforms weighing 21 and 22 kDa also exist, summarized as the FGF-2 high molecular weight (FGF-2HMW) isoform. Meanwhile, the human FGF-2HMW comprises a 22, 23, 24 and 34 kDa protein. Independent studies verified a specific intracellular localization, mode of action and tissue-specific spatiotemporal expression of the FGF-2 isoforms, increasing the complexity of their physiological and pathophysiological roles. In order to analyze their spectrum of effects, FGF-2LMW knock out (ko) and FGF-2HMWko mice have been generated, as well as mice specifically overexpressing either FGF-2LMW or FGF-2HMW. So far, the development and functionality of the cardiovascular system, bone formation and regeneration as well as their impact on the central nervous system including disease models of neurodegeneration, have been examined. This review provides a summary of the studies characterizing the in vivo effects modulated by the FGF-2 isoforms and, thus, offers a comprehensive overview of its actions in the aforementioned organ systems.     

Distributed wireless power transfer in sensor networks with multiple Mobile Chargers

We investigate the problem of efficient wireless power transfer in wireless sensor networks. In our approach, special mobile entities (called the Mobile Chargers) traverse the network and wirelessly replenish the energy of sensor nodes. In contrast to most current approaches, we envision methods that are distributed and use limited network information. We propose four new protocols for efficient charging, addressing key issues which we identify, most notably (i) what are good coordination procedures for the Mobile Chargers and (ii) what are good trajectories for the Mobile Chargers. Two of our protocols (DC, DCLK) perform distributed, limited network knowledge coordination and charging, while two others (CC, CCGK) perform centralized, global network knowledge coordination and charging. As detailed simulations demonstrate, one of our distributed protocols outperforms a known state of the art method, while its performance gets quite close to the performance of the powerful centralized global knowledge method.     

催化裂化装置沉降器内结焦物的基本特性分析及其形成过程的探讨

采用扫描电镜（SEM）和X射线能谱分析仪对催化裂化装置（FCCU）沉降器内结焦物的微观组织结构和成分进行了分析，将结焦物划分为软焦和硬焦。焦的硬度与油气液滴和催化剂颗粒的沉积过程有关，尤其是结焦部位的油气流动方式和催化剂颗粒的运动状态，决定着未汽化的重质油组分液滴和催化剂颗粒的沉积形式和沉积物的构成，从而影响着焦的软硬程度。软焦是催化剂颗粒或油气在油气静止空间以自由沉降和扩散方式堆积在器壁表面而产生的结焦，形成的焦块松散，易粉碎，含催化剂比较多，颗粒粒径比较大，是一种堆积型结焦；而硬焦是油气液滴和细小催化剂颗粒在油气流动状态下，在器壁表面的附面层内以沉积方式粘附在器壁表面形成的结焦，焦块质地坚硬，含催化剂比较少。颗粒粒径细小，足沉积型结焦。还有相当一部分结焦物介于软焦和硬焦之间。     

Cu基络合物催化甲醇液相氧化羰化反应

针对甲醇液相氧化羰基化法合成碳酸二甲酯(DMC)工艺,开发了新型Cu基络合催化剂(CuB rnLm)。对CuB rnLm催化剂的活性及其稳定性进行了研究。实验结果表明,采用该催化剂,甲醇转化率和DMC选择性较高;元素价态和物质结构分析表明,CuB rnLm催化剂循环使用5次后仍保持较好的稳定性。采用正交设计和中心响应曲面法设计实验,并使用S tatistica软件进行统计分析,寻求出反应的主要影响因素,并得到优化的工艺条件:反应温度100~110℃、反应压力3.0~3.5M Pa、反应时间4~6h、CuB rnLm催化剂质量浓度(以甲醇的体积计)0.15~0.20g/mL。在此工艺条件下,甲醇转化率可达23%以上,DMC的选择性为96%~98%。     

TUD-DNS3脱硝助剂在催化裂化装置的工业应用

TUD-DNS3脱硝助剂在中韩（武汉）石油化工有限公司1号催化裂化装置上进行了工业应用。结果表明：针对两段再生工艺，当系统中助剂占总催化剂藏量的质量分数为2.6%时，烟气脱硫装置外排污水中的氨氮质量浓度由加剂前的100 mg/L下降至40 mg/L以内；助剂的加入降低了CO焚烧炉的炉膛温度，有利于烟气的合格排放，并对装置操作、产品分布及汽油、柴油产品质量无不良影响。     

Skeletal Isomerization and Inter—molecular Hydrogen Transfer Reactions in Catalytic Cracking

Bimolecular hydrogen transfer and skeletal isomerization the important secondary reac-tions among catalytic cracking reactions,which affect product yield distribution and product quality,Catalyst properties and operating parameters have great impact on bimolecular hydrogen transfer and skeletal isomerization reactions .Bimolecular hydrogen transfer activity and skeletal isomrization activity of USY-containing catalysts are higher thn that of ZSM-5-containing catalyst.Coke deposition on the active sites of catalyst may suppress bimolecular hydrogen transfer activity and skeletal isomer-ization activity of catlys in different degrees.Short raction time causes a decrease of hydrogen trans-fer reaction,but and increase of skeletal isomerization reaction compared to cracking reaction in catalytic cracking process.     

基于充放电原理实现的微电容测量电路

具有抗分布电容以及简单实用等特性的充放电电路是目前微电容测量中广泛采用的一种测量电路。本文对基于充放电原理的微电容测量电路进行了深入研究，并介绍一种基于充放电原理的实用电路。     

中关村中心区水文地质及工程地质特征

本文全面、系统地分析了北京市中关村中心区的水文地质及工程地质特征 ,为该地区的工程建设提供可靠的地质资料     

减压渣油与FCC油浆共炭化的化学组成变化

考察了齐鲁石化胜利炼油厂催化油浆（FCC）和胜利减压渣油（VR）在490℃，0.8MPa下不同混合比的原料和不同反应时间的中间产物的HS、TS、PS、P及其1h中间产物的HS和TS的^1H-NMR。数据结果反映了体系的反应速度。掺入FCC油浆抑制了VR的反应活性，降低了体系的反应速度，增加了基质的溶解度；1h中间产物的组成结构更接近于原料及反应体系的反应性和基质的溶解度；1h中间产物的芳香度越高，取代基越少，侧链越短，基质对VR中的活性反应组分在炭化早期生成的高度缩合物质的溶解度越大。     

首钢外购焦炭质量恶化后的高炉生产实践

针对焦炭质量劣化的状况，高炉操作以活跃炉缸为主，从上下部调剂入手，采取疏导煤气、控制合理的实际风速和鼓风动能、缓解焦炭在高温区的粉化等措施，有效地改善了高炉的顺行状况，并逐步恢复高炉指标。