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排序方式: 共有5046条查询结果,搜索用时 46 毫秒
1.
Ligang Yu Yong Li Yukun Yang Caixia Guo Meiping Li 《International Journal of Food Science & Technology》2022,57(7):4646-4655
This study investigated the inhibitory effects of curcumin and piperine on fluorescent advanced glycation end products (fAGEs) formation in a bovine serum albumin (BSA)–fructose model. Model systems of BSA and fructose were prepared, and curcumin or piperine was added. fAGEs and BSA oxidation product (dityrosine, kynurenine and N'-formylkynurenine) contents were determined. The results showed that fAGEs content decreased with increasing concentration of curcumin and piperine (P < 0.05). Addition of curcumin and piperine at 160 µg mL−1 could inhibit fluorescent AGEs by 100% and 93% respectively. Dityrosine and N'-formylkynurenine contents decreased as curcumin and piperine concentration increased (P < 0.05). Furthermore, the result of principal component analysis indicated that curcumin and piperine markedly impeded BSA oxidation, resulting in a lower level of fAGEs in model systems. Therefore, adding curcumin and piperine may facilitate reduced fAGEs levels in BSA–fructose model. 相似文献
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Qiaozhi Zhang Yanbo Wang Linglin Fu 《Comprehensive Reviews in Food Science and Food Safety》2020,19(5):2559-2587
Dietary advanced glycation end products (dAGEs) are complex and heterogeneous compounds derived from nonenzymatic glycation reactions during industrial processing and home cooking. There is mounting evidence showing that dAGEs are closely associated with various chronic diseases, where the absorbed dAGEs fuel the biological AGEs pool to exhibit noxious effects on human health. Currently, due to the uncertain bioavailability and rapid renal clearance of dAGEs, the relationship between dAGEs and biological AGEs remains debatable. In this review, we provide the most updated information on dAGEs including their generation in processed foods, analytical and characterization techniques, metabolic fates, interaction with AGE receptors, implications on human health and reducing strategies. Available evidence demonstrating a relevance between dAGEs and food allergy is also included. AGEs are ubiquitous in foods and their contents largely depend on the reactivity of carbonyl and amino groups, along with surrounding condition mainly pH and heating procedures. Once being digested and absorbed into the circulation, two separate pathways can be involved in the deleterious effects of dAGEs: an AGE receptor‐dependent way to stimulate cell signals, and an AGE receptor‐independent way to dysregulate proteins via forming complexes. Inhibition of AGEs formation during food processing and reduction in the diet are two potent approaches to restrict health‐hazardous dAGEs. To elucidate the biological role of dAGEs toward human health, the following significant perspectives are raised: molecular size and complexity of dAGEs; interactions between unabsorbed dAGEs and gut microbiota; and roles played by concomitant compounds in the heat‐processed foods. 相似文献
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Xu You-heng Dong Li-yun Huang Dong-qun Fudan University Shanghai P. R. China 《水动力学研究与进展(B辑)》1998,(3)
In this paper,the oscillation amplitude of the free end of a group of threecylinders are studied.The three cylinders are erected at the vertices of an equilateral trian-gle,and three arrangements are made in this study.One of the three cylinders is served asa working cylinder which is mounted by a flexible cantilever and two accelerometers areattached on the free end in two directions.The results of the three-cylinder arrangementare compared with those of two cylinders in tandem/side-by-side arrangement in the samecondition.The experimental results show that the rear cylinder of a group of three cylin-ders is affected more seriously than that of the corresponding two cylinders in the contrastarrangement.The main direction of oscillation is changed.The transversal oscillation isstronger than the longitudinal oscillation in the three-cylinder arrangement.On the con-trary,the transversal oscillation is much weaker than the longitudinal oscillation in two-cylinder arrangement.The largest transversal oscillat 相似文献
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介绍燕山石化公司为扩大1Mt/a中压加氢改质装置的原料来源,改用大庆减二线油和重油催化裂化柴油组成的混合料开工投产的经验以及装置初期的运行条件。中压加氢改质技术可以生产优质柴油和蒸汽裂解制乙烯的原料,还可增产喷气燃料。 相似文献
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Haley William E.; Larson Dale G.; Kasl-Godley Julia; Neimeyer Robert A.; Kwilosz Donna M. 《Canadian Metallurgical Quarterly》2003,34(6):626
Professional psychologists are increasingly likely to encounter opportunities to work with patients and families facing end-of-life issues. Psychologists can provide psychological assessment, intervention for patients and families, consultation with and support of health care team members, grief therapy, and program development and evaluation. Psychological services are useful for healthy individuals who wish to make thoughtful plans about their own future care, patients with life-limiting illnesses, families stressed by providing end-of-life care, bereaved individuals, and health care providers who face issues of burnout and strain. Several challenges for psychologists working in end-of-life care are noted, including training, development of clear roles, and reimbursement. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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