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Adults' response to Massachusetts anti-tobacco television advertisements: impact of viewer and advertisement characteristics
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OBJECTIVE: To assess adults' receptivity to the Massachusetts television anti-tobacco campaign. Reactions were examined as a function of respondents' demographics, baseline tobacco control attitudes, changes in smoking status during the campaign, and advertisements' affective qualities. DESIGN: A random digit dial telephone survey in 1993 at the start of the media campaign and re-interview in 1996 of respondents to the baseline survey. PARTICIPANTS: Respondents were 1544 adults who completed the baseline and follow up interview. INTERVENTION: By the time the follow up survey was completed, approximately $49 million had been spent on the media campaign. Approximately 66 spots had been aired. MAIN OUTCOME MEASURES: Reported exposure to television advertisements; perceived effectiveness of nine specific advertisements each. RESULTS: 56% of respondents reported seeing anti-tobacco advertisements at least once a week during the preceding three years. The average effectiveness rating for all advertisements recalled on a 0-10 scale was 7.29, and did not differ by smoking status group. Advertisements eliciting strong negative emotions (sadness and fear) were rated most effective by quitters, non-smokers, and by smokers who at baseline were planning to quit soon. Humorous, entertaining advertisements were seen as ineffective by all groups. CONCLUSION: The Massachusetts anti-tobacco campaign achieved high levels of penetration into the population and was well received by both smokers and non-smokers. The results suggest that advertisements depicting suffering as a result of tobacco use may be instrumental in promoting cessation or reinforcing the decision to quit. Further research is needed to lend additional support to the link between perceived effectiveness and smoking behaviour change. 相似文献
3.
Tall larkspur (Delphinium spp.) is a palatable but toxic poisonous plant in the western United States. The toxins in tall larkspur are diterpenoid alkaloids. We examined the influences of food flavor and postingestive consequences on consumption of a 33% larkspur pellet during 30-min feeding periods for five days using esophageally fistulated cattle that were sham-fed larkspur pellets. Consumption by the sham-fed group was compared to a control group fed alfalfa pellets, and a larkspur group fed only larkspur pellets. Sham-fed cattle did not decrease (P > 0.1) feed consumption compared to controls, indicating no significant difference in food flavor. The larkspur group decreased (P < 0.05) feed consumption by 41% relative to controls and by 31% relative to sham-fed animals (P = 0.08). This reduction in feed consumption indicates the adverse postingestive consequences of tall larkspur ingestion, as the larkspur group apparently developed a conditioned taste aversion to the larkspur pellet. Even though these animals were averted to the pellets, they showed none of the classical signs of intoxication from ingestion of tall larkspur.This research was supported in part by the Utah Agricultural Experiment Station, Utah State University, Logan, Utah 84322. Approved as journal article No. 3846. 相似文献
4.
针对两轮自平衡机器人的运动平衡控制问题,采用了基于Skinner操作条件反射理论的自回归神经网络学习算法作为机器人的学习机制,利用自回归神经网络对评价函数进行逼近,以实现对行为决策的优化,从而使机器人能够在无需外部环境模型的情况下,通过学习和训练,获得像人或动物一样的自主学习技能,解决了两轮机器人的运动平衡控制问题.最后分别在无扰动和有扰动的两种状态下设计了仿真实验并进行了比较.结果表明,该操作条件反射学习机制具有较快的自主平衡控制技能和较好的鲁棒性能,体现了较高的理论研究意义和工程应用价值. 相似文献
5.
Discrimination among differentially rewarding flowers allows honeybees to maximize their foraging efficiency. We studied how honeybees are able to relate to differential positive rewards when the odor representations are either structurally dissimilar, structurally similar (or form a substrate–product duo in planta), or form a binary mixture sharing a common constituent. Bees were tested both in conditioning of the proboscis-extension response (PER) and in a free-flying context. Our results point to honeybees using olfactory associative learning to differentiate between two positively rewarded odors. In PER, subjects discriminated best between dissimilar odors; they initially generalized between similar odors, but eventually learned to discriminate between them. The discrimination between mixtures sharing a common constituent remained poor. Likewise, the difference in visits to low- and high-rewarding flowers of free-flying bees was greater for dissimilar odors than for binary mixtures sharing a common constituent. Consequences of the operant conditioning nature of the free-flying context are discussed. 相似文献
6.
With the rapid development of artificial intelligence (AI), AI anxiety has emerged and is receiving widespread attention, but research on this topic is not comprehensive. Therefore, we investigated the dimensions of AI anxiety using the theoretical model of integrated fear acquisition and a questionnaire survey. A total of 494 valid questionnaires were recovered. Through a first-order confirmatory factor analysis (CFA), a factor model of AI anxiety was constructed, and eight factors of AI anxiety were verified. Then, a second-order CFA was applied to verify the adaptation of the factor structure of AI anxiety to fear acquisition. We identified four dimensions of AI anxiety and proposed a theory of AI anxiety acquisition that illustrates four pathways of AI anxiety acquisition. Each pathway includes two factors that cause AI anxiety. We conclude by analyzing the limitations of current AI anxiety research and proposing a broader research agenda for AI anxiety. 相似文献
7.
New technologies offer employers the ability to replace tasks done by human labour with those done by machines. There are challenges for both employers and employees, as employers look for strategies for the implementation of automation technologies and employees may have concerns about their employment being threatened by automation technologies. In this research, we analyse data of over 500 Bulgarians to learn about how they perceive the automation of their jobs. The analysis finds that there are segments of the population defined by demographics and attitudes that are more fearful of the automation of their jobs than others. Additionally, we see that attitudes towards the dehumanizing effects of automation, peer-pressure, job automatability, and a person's self-perception of professionalism are the main drivers of the fear of automation. Finally, the paper evaluates respondents' attitudes towards various individual, corporate and social solutions to automation fears. 相似文献
8.
Hypoxia regulates fibroblast function by changing intracellular signaling and secretion factors, that influence the states of nearby cells. In this work, we investigated how medium (CM) from human adult dermal fibroblasts (HDFs) cultured in normoxic and hypoxic conditions affected cervical cancer (HeLa) cells. The HeLa cells showed decreased cell viability, increased apoptosis, and cell cycle arrest in response to CM from hypoxic-cultured HDFs (H-CM) compared with CM from normoxic-cultured HDFs (N-CM). Among the proteins up-regulated (>2-fold) in H-CM compared with N-CM, lymphotoxin-beta receptor (LTBR) decreased the viability of HeLa cells. Among the intracellular proteins down-regulated (>2-fold) in HeLa cells treated with H-CM compared with N-CM, the most enriched biological process GO term and KEGG pathway were protein deubiquitination and hsa05166:HTLV-I infection, respectively. In the protein–protein interaction network of intracellular proteins with altered expression (>2-fold), 1 up-regulated (TNF) and 8 down-regulated (ESR1, MCL1, TBP, CD19, LCK, PCNA, CHEK1, and POLA1) hub proteins were defined. Among the down-regulated hub proteins, the most enriched biological process GO term and KEGG pathway were leading strand elongation and hsa05166:HTLV-I infection, respectively. This study reveals that H-CM had stronger anti-cancer effects on cervical cancer cells than N-CM and induced intracellular signaling patterns related to those enhanced anti-cancer effects. 相似文献
9.
Tatyana Strekalova Dmitrii Pavlov Alexander Trofimov Daniel C. Anthony Andrei Svistunov Andrey Proshin Aleksei Umriukhin Alexei Lyundup Klaus-Peter Lesch Raymond Cespuglio 《International journal of molecular sciences》2022,23(4)
The phenomenon of individual variability in susceptibility/resilience to stress and depression, in which the hippocampus plays a pivotal role, is attracting increasing attention. We investigated the potential role of hippocampal cyclooxygenase-2 (COX-2), which regulates plasticity, neuroimmune function, and stress responses that are all linked to this risk dichotomy. We used a four-week-long chronic mild stress (CMS) paradigm, in which mice could be stratified according to their susceptibility/resilience to anhedonia, a key feature of depression, to investigate hippocampal expression of COX-2, a marker of microglial activation Iba-1, and the proliferation marker Ki67. Rat exposure, social defeat, restraints, and tail suspension were used as stressors. We compared the effects of treatment with either the selective COX-2 inhibitor celecoxib (30 mg/kg/day) or citalopram (15 mg/kg/day). For the celecoxib and vehicle-treated mice, the Porsolt test was used. Anhedonic (susceptible) but not non-anhedonic (resilient) animals exhibited elevated COX-2 mRNA levels, increased numbers of COX-2 and Iba-1-positive cells in the dentate gyrus and the CA1 area, and decreased numbers of Ki67-positive cells in the subgranular zone of the hippocampus. Drug treatment decreased the percentage of anhedonic mice, normalized swimming activity, reduced behavioral despair, and improved conditioned fear memory. Hippocampal over-expression of COX-2 is associated with susceptibility to stress-induced anhedonia, and its pharmacological inhibition with celecoxib has antidepressant effects that are similar in size to those of citalopram. 相似文献
10.
Fear memory helps animals and humans avoid harm from certain stimuli and coordinate adaptive behavior. However, excessive consolidation of fear memory, caused by the dysfunction of cellular mechanisms and neural circuits in the brain, is responsible for post-traumatic stress disorder and anxiety-related disorders. Dysregulation of specific brain regions and neural circuits, particularly the hippocampus, amygdala, and medial prefrontal cortex, have been demonstrated in patients with these disorders. These regions are involved in learning, memory, consolidation, and extinction. These are also the brain regions where new neurons are generated and are crucial for memory formation and integration. Therefore, these three brain regions and neural circuits have contributed greatly to studies on neural plasticity and structural remodeling in patients with psychiatric disorders. In this review, we provide an understanding of fear memory and its underlying cellular mechanisms and describe how neural circuits are involved in fear memory. Additionally, we discuss therapeutic interventions for these disorders based on their proneurogenic efficacy and the neural circuits involved in fear memory. 相似文献