油田放射性作业人员外周血淋巴细胞染色体畸变的观察

本文调查了油田212例受γ射线和中子混合辐射照射的作业人员和30例正常人的外周血淋巴细胞染色体畸变。作业人员受γ射线照射的人均年受照剂量为1.28mGy。调查结果表明,放射性测井人员与正常人相比染色体畸变率有显著差异。     

稀疏脉冲反演技术在井间地震反演中的应用

将传统的波阻抗反演技术应用于井间地震资料反演时，存在着方法适用的域和资料的域不同，井间地震资料的频带比地震资料的频带宽以及频率比地震资料频率高，多对井间地震资料拼接等问题。为此，在胜利油田K71井区，探讨了利用传统波阻抗反演技术（稀疏脉冲反演）进行井间地震资料波阻抗反演的一些技术问题，并用利11对井间地震资料进行了波阻抗反演，获得了较好的反演结果，在井间地震资料反演中，采用匹配滤波方的井间地震资料转换到时间域；利用高分辨率地面三维地震资料，采用统计方法提取反演子波，子波的波形和相位较稳定，频带宽；对测井资料进行标准化处理，在反演的波阻抗剖面上砂体的空间展布形态清晰，对储层的描述更精细；利用时深转换模型，将时间域的波阻抗剖面转换到深度域，直接与测井资料进行对比分析，对储层的描述更直观可靠。     

V. Yeast sequencing reports. Identification of a gene encoding a new Ypt/Rab-like monomeric G-protein in Saccharomyces cerevisiae

A Saccharomyces cerevisiae sequence cloned by serendipity was found to encode a protein that is a new member of the Ypt/Rab monomeric G-protein family. This sequence shows high homology to the yeast genes SEC4 and YPT1 and, like SEC4 and YPT1, is essential for viability. The sequence was localized to chromosome V based upon hybridization to pulse-field gel-separated yeast chromosomes. The sequence has been deposited in the GenBank data library under Accession Number L17070.     

On-line free-flight path optimization based on improved genetic algorithms

Free flight (FF) is the ideal strategy of current investigations on air traffic management systems, where an on-line flight path optimization algorithm is of top importance. This paper proposes an innovative algorithm with potential real-time properties for FF path optimization, by using an improved genetic algorithm (GA). Two kinds of mathematical models for the on-line flight path optimization problem are proposed to cover the near and far future applications. Several improvements are introduced to the GA to speed up its convergence as well as to improve performance. Simulation results show that the new algorithm is effective and has potential to solve the on-line FF path optimization problem in real time.     

Path curvature of a geared seven-bar mechanism

This paper presents a graphical technique to locate the center of curvature of the path traced by a coupler point of a planar, single-degree-of-freedom, geared seven-bar mechanism. Since this is an indeterminate mechanism then the pole for the instantaneous motion of the coupler link; i.e., the point coincident with the instantaneous center of zero velocity for this link, cannot be obtained from the Aronhold–Kennedy theorem. The graphical technique that is presented in the first part of the paper to locate the pole is believed to be an important contribution to the kinematics literature. The paper then focuses on the graphical technique to locate the center of curvature of the path traced by an arbitrary coupler point. The technique begins with replacing the seven-bar mechanism by a constrained five-bar linkage whose links are kinematically equivalent to the second-order properties of motion. Then three kinematic inversions are investigated and a four-bar linkage is obtained from each inversion. The motion of the coupler link of the final four-bar linkage is equivalent up to and including the second-order properties of motion of the coupler of the geared seven-bar. Then the center of curvature of the path traced by an arbitrary coupler point can be obtained from existing techniques, such as the Euler–Savary equation. An analytical method, referred to as the method of kinematic coefficients, is presented as an independent check of the graphical technique.     

Analysis of human chromosome classification using centromere position

Automated homologous classification of human chromosomes from the metaphase spread of a cell is an essential task to identify various genetic disorders. Karyotyping is the process of visualizing and categorizing the chromosomes within a cell. It is very important to have a good feature extraction scheme for proper chromosome classification. Chromosome classification is performed by identifying the morphological features which mainly include the centromere location. The parameter is essential for classification which helps in determining a karyogarm. In this paper, a comparative analysis of two algorithms for identification of centromere position is done. The two approaches make use of the Medial Axis Transformation and Projection Vector. The analysis helps us to identify the algorithm that performs better in the identification of centromere position. The projection vector approach performs well in obtaining the centromere location in the chromosome with an efficiency of 90%.     

高密度电阻率法在园博塔选址勘察中的应用

以隧道与围岩的电性差异为前提,应用高密度电阻率法在第九届中国（北京）国际园林博览会选址区勘探。根据全站仪准确定位和温纳方式现场数据采集,再对数据进行处理和地形校正后,应用Res2dinv高密度电阻率数据二维反演软件完成反演,结合二维地电断面解释结果,定量计算确定了鹰山1号隧道平面分布特征和顶部高程,为拟建园博塔的设计和修建提供了相关的技术依据。     

14.8MeV单能中子所致染色体畸变的剂量-效应关系

采用14.8 MeV单能中子对3名健康成人外周血进行照射,照射剂量分别为0、0.1、0.3、0.6、1.0、2.0、3.0、4.0Gy,观察淋巴细胞染色体畸变情况,建立本实验室染色体畸变与受照剂量的剂量-效应关系.实验结果表明:双着丝粒体+环状体数、无着丝粒体数、总畸变数、畸变细胞率与中子剂量均存在良好的线性关系,回归方程分别为Ydic+r=0.0291+0.0607(r2=0.986)、Yace=0.0124+0.1411D(r2=0.982)、Ya=0.0434+0.2035(r2=0.989)、Yac=0.0362+0.0475D(r2=0.927).     

A new linear time algorithm to compute the genomic distance via the double cut and join distance

The genomic distance problem in the Hannenhalli–Pevzner (HP) theory is the following: Given two genomes whose chromosomes are linear, calculate the minimum number of translocations, fusions, fissions and inversions that transform one genome into the other. This paper presents a new distance formula based on a simple tree structure that captures all the delicate features of this problem in a unifying way, and a linear time algorithm for computing this distance.     

染色体畸变分析作为生物剂量测定方法的研究概况

本文叙述了染色体畸变分析作为生物剂量计的国内外研究概况。文中较详细地介绍了离体照射诱发染色体畸变的剂量-效应关系及其在事故受照人员剂量估算中的应用状况,对局部照射和分次照射条件下确定剂量-效应关系的有关问题进行了分析,对今后研究动向作了简要讨论。