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1.
死亡风险预测指根据病人临床体征监测数据来预测未来一段时间的死亡风险。对于ICU病患,通过死亡风险预测可以有针对性地对病人做出临床诊断,以及合理安排有限的医疗资源。基于临床使用的MEWS和Glasgow昏迷评分量表,针对ICU病人临床监测的17项生理参数,提出一种基于多通道的ICU脑血管疾病死亡风险预测模型。引入多通道概念应用于BiLSTM模型,用于突出每个生理参数对死亡风险预测的作用。采用Attention机制用于提高模型预测精度。实验数据来自MIMIC [Ⅲ]数据库,从中提取3?080位脑血管疾病患者的16?260条记录用于此次研究,除了六组超参数实验之外,将所提模型与LSTM、Multichannel-BiLSTM、逻辑回归(logistic regression)和支持向量机(support vector machine, SVM)四种模型进行了对比分析,准确率Accuracy、灵敏度Sensitive、特异性Specificity、AUC-ROC和AUC-PRC作为评价指标,实验结果表明,所提模型性能优于其他模型,AUC值达到94.3%。 相似文献
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In the past, thinking of carrying electronic devices inside our bodies was only posed by non-real scenarios. The emergence of insertable devices has changed this. Since this technology is still in its initial development stages, few studies have investigated factors that influence its acceptance. This paper analyzes the predictors of the intention to use non-medical insertable devices in two Latin American contexts. We used partial least squares structural equation modeling to examine whether six constructs predicted intention to use insertable devices. A questionnaire was administered to undergraduate students located in Colombia and Chile (n = 672). We also examined whether these predictors influenced intention differently for both of them. Four common constructs significantly and positively influenced both Chilean and Colombian respondents to use insertable devices (hedonic motivation, habit, performance expectancy, and social influence). Also, the habit has a complementary mediating effect on the relationship between social influence and behavioral intention. By contrast, effort expectations were a positive and significant predictor, but only among Chilean respondents. Findings suggest that when technologies are emerging, well-known predictors of intention (e.g., performance and effort expectations) are less influential than predictors related to self-efficacy (e.g., habit and hedonic motivation). The use of insertable devices has a significant impact on society. Thus, a better understanding of what motivates their use has implications for both academia and industry. 相似文献
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为了开发β受体阻断剂新药(S)-噻吗洛尔半水合物,采用3-吗啉-4-氯-1,2,5-噻二唑为起始原料,经水解反应得到中间体1(3-吗啉-4-羟基-1,2,5-噻二唑)。中间体1与R-环氧氯丙烷发生醚化反应,经后处理及重结晶得到中间体2 {(R)-4-[4-(环氧乙烷-2-基甲氧基)-1,2,5-噻二唑-3-基]吗啉}。中间体2经胺化反应、马来酸成盐及重结晶得到(S)-马来酸噻吗洛尔。(S)-马来酸噻吗洛尔经游离、纯水转晶得到符合药典标准的(S)-噻吗洛尔半水合物,总收率14.05%且e.e.值为99.66%。最终成品经IR、1H-NMR、13C-NMR、MS、TGA、DSC表征,并优化各步反应条件。结果表明:以三乙胺为醚化反应缚酸剂75 ℃反应最佳;以乙醇为胺化反应溶剂46 ℃反应16 h最佳;S-噻吗洛尔的转晶拆分以水作溶剂,比传统不对称合成工艺安全稳定,操作简单,适合工业化生产。 相似文献
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This article examines how older adults use and perceive digital technologies in Finland and Ireland. These two countries are at different stages regarding two important global trends – demographic ageing and digitalization. Finland, being the fastest ageing society in Europe, is also one of the leaders in implementing digital technologies in social and health care services. In contrast, Ireland is a demographically younger and less digitalized society. Drawing on focus group discussions on the usage of digital technologies, conducted with older adults in both countries, we analyse how digital technologies are adopted and viewed by older generations. The analyses showed that older adults associate digitalization with both advantages and drawbacks. To encapsulate these two contrasting aspects, we developed the term Janus-faced conceptions of technology. This concept encapsulates how the successful adoption of digital technology facilitates everyday activities whereas the inability to utilise technologies results in feelings of alienation and being out-of-touch. The digital divide was found to occur not only between generations but also between different socioeconomic groups of older adults. 相似文献
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We study a two-stage stochastic and nonlinear optimization model for operating a power grid exposed to a natural disaster. Although this approach can be generalized to any natural hazard of continuous (and not instantaneous) nature, our focus is on wildfires. We assume that an approaching wildfire impacts the power grid by reducing the transmission capacity of its overhead lines. At the time when proactive decisions have to be taken, the severity of the wildfire is not known. This introduces uncertainty. In this paper, we extend previous work by more realistically capturing this uncertainty and by strengthening the mathematical programming formulation through standard reformulation techniques. With these reformulation techniques, the resulting two-stage, convex mixed-integer quadratically constrained programming formulation can be efficiently solved using commercial quadratic programming solvers as demonstrated on a case study on a modified version of the IEEE 123-bus test system with 100 scenarios. We also quantify the uncertainties through a second case study using the following three standard metrics of two-stage stochastic optimization: the expected value of perfect information, the expected result of using the expected value solution and the value of the stochastic solution. 相似文献
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Acknowledging the lack of studies examining both visual and linguistic anthropomorphic cues and the underlying mechanisms of their effects, we investigated how the different modalities of anthropomorphic cues in a health website influenced information disclosure. In a 2 (visual cues: human vs. non-human image) × 2 (linguistic cues: conversational vs. impersonal language) × 2 (question type: less vs. more sensitive questions) between-subjects experiment (N = 254), participants registered with a mock-up health website. We assessed a behavioral outcome of not disclosing personal information and psychological outcomes of social perception and self-awareness as potential mediators. Results revealed distinctive effects of the two modalities of the anthropomorphic cues. Anthropomorphic images, on one hand, increased public and private self-awareness, and public self-awareness in turn led to less information disclosure. Anthropomorphic language, on the other hand, heightened social perception and promoted information disclosure, but social perception did not predict the disclosure. These results indicate unique underlying mechanisms of the effects of anthropomorphism: priming effect of visual cues, and communicative effects of linguistic cues. 相似文献
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目前网络上的服装图像数量增长迅猛,对于大量服装图像实现智能分类的需求日益增加。将基于区域的全卷积网络(Region-Based Fully Convolutional Networks,R-FCN)引入到服装图像识别中,针对服装图像分类中网络训练时间长、形变服装图像识别率低的问题,提出一种新颖的改进框架HSR-FCN。新框架将R-FCN中的区域建议网络和HyperNet网络相融合,改变图片特征学习方式,使得HSR-FCN可以在更短的训练时间内达到更高的准确率。在模型中引入了空间转换网络,对输入服装图像和特征图进行了空间变换及对齐,加强了对多角度服装和形变服装的特征学习。实验结果表明,改进后的HSR-FCN模型有效地加强了对形变服装图像的学习,且在训练时间更短的情况下,比原来的网络模型R-FCN平均准确率提高了大约3个百分点,达到96.69%。 相似文献