PPS：基于PROSITE数据库检索蛋白质功能位点的计算机程序

用标准Ｃ语言在ＩＢＭ－ＰＣ兼容微机上开发了基于ＰＲＯＳＩＴＥ数据库检索蛋白质序列功能位点的ＰＰＳ程序，ＰＲＯＳＩＴＥ是Ｂａｉｒｏｃｈ建立的蛋白质功能位点或结构模式的资料库，为蛋白质序列分析和结构功能研究提供了新工具。     

Motif patterns in 2D

Motif patterns consisting of sequences of intermixed solid and don’t-care characters have been introduced and studied in connection with pattern discovery problems of computational biology and other domains. In order to alleviate the exponential growth of such motifs, notions of maximal saturation and irredundancy have been formulated, whereby more or less compact subsets of the set of all motifs can be extracted, that are capable of expressing all others by suitable combinations. In this paper, we introduce the notion of maximal irredundant motifs in a two-dimensional array and develop initial properties and a combinatorial argument that poses a linear bound on the total number of such motifs. The remainder of the paper presents approaches to the discovery of irredundant motifs both by offline and incremental algorithms.     

Exploiting knowledge ontology and software agents for PPI network analysis

One major goal of functional genomics has been to identify and analyze molecular interactions in a cellular context to better understand the underlying design principles and mechanisms. To investigate into a PPI network from both topological and functional points of view, this work proposes a methodology that exploits ontology-based biological knowledge for network analysis. To speed up the procedure, an agent-based framework is also presented for supporting distributed computing. The preliminary results show that through the knowledge obtained from gene ontology, our work in analyzing building blocks of PPI networks can give a higher resolution than that of previous ones. Also our agent-based framework can successfully speed up the task of network analysis in an adaptive manner.     

X窗口系统中应用程序构造技术探讨

介绍了X窗口系统环境下应用程序界面的自动生成技术,其中包括Motif编程模型及有关概念;应用程序构造器生成应用程序界面的过程;应用程序构造器的机理及构造器创建应用程序的完善。     

Motif analysis for automatic segmentation of CT surface contours into individual surface features

This paper presents a new layer-based technique for automatic high-level segmentation of 3-D surface contours into individual surface features through motif analysis. The procedure starts from a contour-based surface model representing a composite surface area of an object. For each of the surface contours, a relative turning angle (RTA) map is derived. The RTA map usually contains noise and minor features. Algorithms based on motif analysis are applied for extracting a main profile of the RTA map free from background noise and other minor features. All feature points on the extracted profile are further identified from the extracted main profile through further motif analysis. The original contour is thus partitioned into individual segments with the identified feature points. A collection of consecutive contour segments among different layers form an individual 3-D surface feature of the original composite surface. The developed approach using motif analysis is particularly useful for the identification of smooth joins between individual surface features and for the elimination of superposed noise and unwanted minor features.     

Maximal and minimal representations of gapped and non-gapped motifs of a string

The problems of finding maximal and minimal equivalent representations for gapped and non-gapped motifs as well as finding motifs that characterize a fixed set of occurrence locations for a given string are studied. We apply two equivalence relations on representations. The first one is the well-known occurrence-equivalence of motifs. The second equivalence is introduced for patterns of occurrence locations, to characterize such patterns by motifs. For both equivalences, quadratic-time algorithms are given for finding a maximal representative of an equivalence class. Finding a minimal representative is shown to be NP-complete in both cases. For non-gapped motifs suffix-tree-based linear-time algorithms are given for finding maximal and minimal representatives. Maximal (minimal) gapped motifs are composed of blocks that are maximal (minimal) non-gapped motifs, maximal and minimal non-gapped motifs thus making up a small basis for all motifs. The implied bound on the number of gapped motifs that have a fixed number of non-gapped blocks is also given.     

亦古亦今——当代建筑装饰中传统母题的案例研究

建筑的地域性特征,是当代建筑发展的重要趋势之一。在地域性的空间形式和材料工艺之外,含有传统母题的建筑装饰逐渐成为体现地域性特征的有效手段。该文将选取近年来四个建成案例,从以下方面加以分析:1装饰元素自身的形式特征;2传统母题的选取与抽象衍化;3建筑装饰如何与建筑内容与文化背景有机地结合。在案例研究的基础上,归纳传统母题在当代建筑装饰中应用的经验与模式,为建筑实践提供可借鉴的理论依据。     

基于模体演化的多因子动态链路预测方法

为了提高动态网络链路预测准确率,从网络结构微观演化角度,提出基于模体演化的多因子动态链路预测方法(MFME).在动态网络时间窗口划分优化的基础上,引入整合移动平均自回归模型构建预测模体演化的概率矩阵,综合考虑模体演化影响因子及模体演化概率,可获得任意节点间的连接边概率.在真实数据集的实验表明,所提方法能达到更好的链路预...     

西方古典家具装饰题材与内涵

装饰是许多优秀家具常用的手法。装饰题材的选择及处理特点与时代背景、民族心理相关。西方家具的装饰题材随其历史的变迁而演进,不同时代的装饰题材各有特色,题材的内涵由象征化向美化或时尚化方向发展是主要趋势,但有时各种内涵也出现混杂炙错的情形。在某些时代,古典装饰题材还用来表达人文主义、自然主义或理性主义思想。西方家具装饰题材及其内涵的演变符合总体家具文化演进的一般规律。