S698 T处理器的RTEMS移植和应用程序开发

一个简单的星载计算机模型由一个模拟真实卫星的嵌入式系统和系统运行所必需的数据集合组成,该数据集合由PC机上运行的程序生成,模拟真实卫星的运行环境。为了构建这个模型,首先要完成以SPARC V8架构处理器S698 T为基础的 RTEMS操作系统移植,然后分别在S698 T端和 PC端开发对应的应用程序,讨论构建嵌入式系统的主要步骤和需要注意的问题。     

基于TLM2.0的SPARC事务级建模

为提高可扩展处理器体系结构(SPARC)的设计抽象层次和仿真速度,设计一种符合第8版SPARC(SPARC V8)的事务级模型。该模型基于TLM2.0标准,采用解释型指令集仿真方法实现程序执行。通过构建验证环境,证明该事务级模型能够正确运行并跟踪SPARC V8程序,仿真速度比寄存器传输级提高2个数量级。     

国产32位S698处理器的嵌入式教学平台

介绍一种基于S698处理器的嵌入式系统教学平台,平台针对嵌入式系统开放式、设计型教学的特点进行设计;详细描述教学平台的硬件系统设计和软件实现。该教学平台具有易学习,简洁美观,方便实用等特点。     

SUN的SPARC处理器体系结构及TurboSPARC微处理器

本文介绍了Sun Microsystems公司的SPARC处理器体系结构以及TurboSPARC微处理器,详细叙述了其技术特征及优化性能。     

RTEMS移植到SAILING S698处理器的开发环境配置

RTEMS是一款优秀的实时嵌入式操作系统,它支持多种处理器架构,具有良好的可移植性和裁剪性,支持多种API标准以及开源的特点,使得它被广泛应用在多种嵌入式领域.以基于SPARC V8架构的S698处理器开发板为目标,分析了RTEMS移植到S698的主要过程,描述了开发环境的配置方法,并以RTEMS标准例程验证开发环境的正确性.     

SPARC研究进展

SPARC是一种具有多种功能的小分子酸性糖蛋白,在机体内分布广泛。它是SPARC蛋白家族的一员,有FS、EC保守区。SPARC通过与胞外基质的相互作用表现出多种生物学活性,其中最主要的是调节细胞增殖和抗粘附作用。SPARC的这些功能对某些疾病过程如肿瘤的侵袭性、外伤的修复等起着重要的作用。SPARC的各种功能与其结构特征密切相关,但它的具体作用机制不明确,需要深入研究。本文就SPARC基因的结构特征、生理功能等方面问题进行了综述,并对SPARC基因的研究进行了展望。     

Looking to the future: biomarkers in the management of pancreatic adenocarcinoma

The incidence and mortality of pancreas cancer converge. There has been little advancement in the treatment of pancreas cancer since the acceptance of gemcitabine as the standard therapy. Unfortunately, the efficacy of gemcitabine is dismal. While there is much discussion for the development of biomarkers to help direct therapy in this area, there is little action to move them into clinical practice. Herein, we review potential pancreatic cancer biomarkers and discuss the limitations in their implementation.     

一种改进的数据通信协议设计与实现

在主机与目标机间建立与通信端口无关的命令驱动式数据通信协议,给出数据包格式及命令功能定义。该协议采用分层和模块化设计方法,支持1553B和RS-232 2种通信端口,通过扩展底层通信管理模块可实现对CAN、SPI、SPACEWIRE等总线的支持。SPARC V8存储器加载和下载软件的运行结果验证该协议的正确性,表明其能屏蔽不同通信端口之间的差异性,实现正常的数据传输。     

High SPARC Expression Starting from Dysplasia,Associated with Breast Carcinoma,Is Predictive for Bone Metastasis without Enhancement of Plasma Levels

In order to become established in the skeleton, metastatic cells disseminating from the breast carcinoma need to acquire organ-specific traits. There are no effective predictors for who will develop bone metastasis to guide long-term predictive therapy. Our purpose was to individuate events critical for bone colonization to make a molecular classification of breast carcinoma useful for bone-metastasis outcome. In dysplasia adjacent to carcinoma and in pair-matched specimens of bone metastasis we examined SPARC expression and localization as well as Endothelin 1/ET_AR signals by immunohistochemistry, and the evaluation of plasma levels of SPARC by ELISA was also performed. In patients with breast carcinoma metastasizing to bone, SPARC and Endothelin 1/ET_AR axis were highly expressed from dysplasia until bone metastasis, but the SPARC plasma level was as low as that of normal women, in contrast to patients that never develop bone metastasis, suggesting that circulating SPARC was counter adhesive. Altogether, the early identification of SPARC/Endothelin 1/ET_AR in dysplastic lesions would be important to devise therapies preventing metastasis engraftment, since often carcinoma cells spread to distant organs at the time or even before patients present with cancer.     

S698P4 SoC芯片存储器控制器的设计与实现

详细分析了S698P4 SoC芯片存储器控制器的控制原理,并给出相应设计方案和仿真结果。该控制器可在32bit位宽模式下对存储器进行读写控制。目前该处理器已实现了量产,实际硬件测试验证了S698P4 SoC芯片存储器控制器的高效性能。