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Donepezil Regulates LPS and Aβ-Stimulated Neuroinflammation through MAPK/NLRP3 Inflammasome/STAT3 Signaling |
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| Authors: | Jieun Kim Hyun-ju Lee Seon Kyeong Park Jin-Hee Park Ha-Ram Jeong Soojung Lee Heeyong Lee Eunyoung Seol Hyang-Sook Hoe |
| Affiliation: | 1.Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), 61, Cheomdan-ro, Dong-gu, Daegu 41062, Korea; (J.K.); (H.-j.L.); (S.K.P.); (J.-H.P.); (H.-R.J.);2.G2GBIO, Inc., Science Park #411, 1646 Yuseong-daero, Yuseong-gu, Daejeon 34054, Korea; (S.L.); (H.L.); (E.S.);3.Department of Brain and Cognitive Science, Daegu Gyeongbuk Institute of Science & Technology (DGIST), 333, Techno Jungang-daero, Hyeonpung-eup, Dalseong-gun, Daegu 42988, Korea |
| Abstract: | |
| Keywords: | donepezil rivastigmine astrocyte microglia ROS NLRP3 inflammasome STAT3 |