气相色谱法测定防晒化妆品中14种防晒剂的含量

采用甲醇超声萃取防晒化妆品中防晒剂,经DB-5MS毛细管色谱柱分离,氢火焰离子化检测器测定,建立了气相色谱法同时测定防晒化妆品中14种防晒剂的检测方法。结果表明:14种防晒剂在0.5~100.0mg/kg范围内线性关系良好,相关系数(r~2)≥0.9993;检出限为0.05~0.15mg/kg,定量限为0.17~0.50mg/kg;加标回收率为91.7%~100.1%,相对标准偏差为1.1%~3.1%。该法操作简便、加标回收率高、精密度好、检出限低,可为防晒化妆品中防晒剂的种类和含量测定提供参考。

Determination of 14 sunscreen agents in sunscreen cosmetics by gas chromatography

A method for simultaneous determination of 14 sunscreen agents in sunscreen cosmetics was established by gas chromatography, with ultrasonic extraction of sunscreen agents in sunscreen cosmetics carried out by DB-5MS capillary column separation and hydrogen flame ionization detector. The results show that the linearity of 14 sunscreen agents is good in the range of 0.5-100.0 mg/kg, and the correlation coefficients are more than 0.999 3. The detection limit is 0.05-0.15 mg/kg, the limit of quantification is 0.17-0.50 mg/kg; the relative standard deviation is 1.1%-3.1%, and the recovery rate of the spiked standards are 91.7%-100.1%. The method has the advantages of simple operation, high recovery rate, good precision and low detection limit, and can provide a detection method for determining the type and content of the sunscreen agent in the sunscreen cosmetic.