玻璃基多孔骨水泥的制备和性能研究

将SiO2-CaO-P2O5系统生物活性玻璃粉末、甘露醇和磷酸铵调和液均匀混合制得多孔玻璃基骨水泥.利用XRD、FTIR和SEM对骨水泥的晶相和显微结构进行了观察和分析,并对其显气孔率和力学强度进行了测试.实验结果表明,随着浸泡时间的增加,骨水泥固化体中生成了HAP晶体,HAP晶体呈短柱状,交织分布于玻璃颗粒间隙,尺寸大约为200nm;甘露醇晶体能在生理模拟液的浸泡下降解,降解后留下的孔隙显著增加了骨水泥的显气孔率,并且随着甘露醇含量的增加而增加,而体积密度和力学强度则呈下降的趋势.

Preparation and property investigation of glass-based porous bone-cement

In this study,the porous glass-based bone cement was synthesized by evenly stirring the mixture of bioactive SiO_2-CaO-P_2O_5 system glass powder,mannitol and liquid medium,that is ammonium phosphate solution.Crystalline form,chemical composition and microstructure of the porous bone cement were investigated by XRD,FTIR and SEM respectively.And the apparent porosity was also measured.The results indicate that along with immersion in the simulated body fluid(SBF),there formed bone-like crystal HAP in the porous cement.The demention of these HAP crystals,interlacing with each other among glass granules,is about 200nm.The degradation of mannitol enhances the apparent porosity of bone cement,and the value increases with the content of mannitol,but opposite are bulk density and mechanical properties.