| N-[(4-溴-3,5-二氟)苯基]丙烯酰胺的合成与表征 |
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| 引用本文： | 姚新鼎,李延勋,徐丽,雒廷亮,刘国际.N-[(4-溴-3,5-二氟)苯基]丙烯酰胺的合成与表征[J].精细石油化工,2010,27(4). |
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| 作者姓名： | 姚新鼎 李延勋 徐丽 雒廷亮 刘国际 |
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| 作者单位： | 郑州大学化工与能源学院; |
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| 基金项目： | 河南省重大科技攻关项目，河南省教育厅自然科学研究计划项目 |
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| 摘 要： | 实验以丙烯酰氯和4-溴-3,5-二氟苯胺为原料,在三乙胺催化下合成了含氟丙烯酰胺单体N-(4-溴-3,5-二氟)苯基]丙烯酰胺。该单体经红外光谱、质谱、~1H NMR和~(13)C NMR进行了表征,探讨了各步反应的影响因素。最佳工艺条件为:催化剂三乙胺用量为投料总质量的1.15%,反应时间4 h,反应温度0℃,n(丙烯酰氯):n(4-溴-3,5-二氟苯胺)=1.1:1。产物质量收率为62.5%。
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| 关 键 词： | N-[(4-溴-3 5-二氟)苯基]丙烯酰胺 丙烯酰氯 酰胺化 |
SYNTHESIS AND CHARACTERIZATION OF N-[(4-BROMO-3,5-DIFLUORINE)PHENYL] ACRYLAMIDE |
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| Yao Xinding,Li Yanxun,Xu Li,Luo Tingliang,Liu Guoji.SYNTHESIS AND CHARACTERIZATION OF N-[(4-BROMO-3,5-DIFLUORINE)PHENYL] ACRYLAMIDE[J].Speciality Petrochemicals,2010,27(4). |
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| Authors: | Yao Xinding Li Yanxun Xu Li Luo Tingliang Liu Guoji |
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| Affiliation: | Yao Xinding,Li Yanxun,Xu Li,Luo Tingliang and Liu Guoji (School of Chemical and Energy Engineering,Zhengzhou University,Zhengzhou 450001,He'nan,China) |
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| Abstract: | Under the catalysis of triethylamine,acryloyl chloride reacted with 4-Bromo-3,5-difluoroan-iline for 4 h at 0℃to yield N-(4-Bromo-3,5-difluorine)phenyl]acrylamide.The chemical structure of the product was confirmed by means of FT-IR,~1H NMR,~(13)C NMR and mass spectroscopy.Various influencing factors on the reactions were also investigated and discussed.The optimum reaction conditions were found as follows:w(TEA) = l.15%,reaction temperature 0℃,reaction time 4 h, molar ratio of n(acryloyl chloride) to n(4-Bromo-3,5-difluoroaniline) of 1.1.Under these conditions, the yield of N-(4-bromo-3,5-difluorine)phenyl]acrylamide was 62.5%. |
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| Keywords: | N-[(4-bromo-3 5-difluorine)phenyl]acrylamide acryloyl chloride amidation |
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