Magnetic Hydrogels and Their Potential Biomedical Applications |
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| Authors: | Yuhui Li Guoyou Huang Xiaohui Zhang Baoqiang Li Yongmei Chen Tingli Lu Tian Jian Lu Feng Xu |
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| Affiliation: | 1. Biomedical Engineering and Biomechanics Center, Xi'an Jiaotong University, Xi'an, 710049, China;2. State Key Laboratory of Space Biotechnology, Northwestern Polytechnical University, Xi'an, 710072, China;3. MOE Key Laboratory of Biomedical Information Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, China;4. Institute for Advanced Ceramics and State, Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, 150001, China;5. MOE Key Laboratory for Non‐Equilibrium Synthesis and Modulation of Condensed Matter, Department of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an, 710049, China |
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| Abstract: | Hydrogels find widespread applications in biomedical engineering due to their hydrated environment and tunable properties (e.g., mechanical, chemical, biocompatible) similar to the native extracellular matrix (ECM). However, challenges still exist regarding utilizing hydrogels in applications such as engineering 3D tissue constructs and active targeting in drug delivery, due to the lack of controllability, actuation, and quick‐response properties. Recently, magnetic hydrogels have emerged as a novel biocomposite for their active response properties and extended applications. In this review, the state‐of‐the‐art methods for magnetic hydrogel preparation are presented and their advantages and drawbacks in applications are discussed. The applications of magnetic hydrogels in biomedical engineering are also reviewed, including tissue engineering, drug delivery and release, enzyme immobilization, cancer therapy, and soft actuators. Concluding remarks and perspectives for the future development of magnetic hydrogels are addressed. |
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| Keywords: | magnetic hydrogels magnetic nanoparticles (MNPs) controllability response properties biomedical engineering |
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