Nucleoside-based phospholipids and their liposomes formed in water |
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Authors: | Choi Seung Kyu Vu Tran Khac Jung Jin Mi Kim Su Jeong Jung Hun Rok Chang Taihyun Kim Byeang Hyean |
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Affiliation: | Department of Chemistry, Division of Molecular and Life Sciences, Pohang University of Science and Technology, San 31 Hyoja Dong, Pohang 790-784, South Korea. |
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Abstract: | Phospholipids and liposomes have been the subjects of considerable attention because of their importance in biological systems. We have efficiently synthesized novel nucleoside-based phospholipids in six-step sequences starting from their corresponding nucleosides. These nucleoside-based phospholipids self-assemble into liposome-like structures in aqueous solutions. We have analyzed the structures of these liposomes by dynamic light scattering, transmission electron microscopy, and confocal microscopy. |
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Keywords: | liposomes nucleosides phospholipids self‐asssembly supramolecular chemistry |
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