固相离子交换法制备高效载银分子筛抗菌剂及其抗菌性能

以小粒径NaA分子筛为载体,硝酸铵和硝酸银为原料,采用固相离子交换法制备载银分子筛抗菌剂。研究AgNO_3的用量、反应温度和反应时间对载银分子筛载银量的影响。分析了载银分子筛的物相和形貌,考察了载银分子筛的抗菌性能、缓释性能及抗变色性能。结果表明,在反应体系n(NH_4A)∶n(AgNO_3)为1∶2,反应温度为400℃,反应时间为4h条件下制备的载银分子筛,其载银量达到(41.35±0.42)%(质量分数),对大肠杆菌(Escherichia coli)的最小抑菌浓度(Minimum inhibitory concentration,MIC)为10.42×10~(-6),杀菌率达到(98.36±0.28)%,抑菌圈直径为15.8 mm;对金黄色葡萄球菌(Staphylococcus aureus)的MIC值为12.50×10~(-6),杀菌率达到(97.43±0.19)%,抑菌圈直径为13.6mm。所制备的载银分子筛具有良好的缓释性能和抗变色性能。

Preparation of Highly Active Ag-loaded Zeolite Antimicrobial by Solid PhaseIonic Exchange Method and Its Antibacterial Properties

The Ag-loaded antibacterial zeolite was prepared by solid phase ionic exchange method with small particle size of NaA zeolite as carrier,NH4NO3 and AgNO3 as raw material.The influence of the AgNO3 amount,reaction temperature,and reaction time on the amount of silver load in the zeolite were investigated.The phase composition and morphology of Ag-loaded zeolite were characterized.The antibacterial property,sustained-release performance,and anti-tarnish property of Ag-loaded zeolite were studied.The results showed that the Ag-loaded zeolite synthesized under optimum conditions (i.e.,the molar ratio n (NH4A) ∶n (AgNO3)=1∶2,reaction temperature was 400 ℃,reaction duration was 4 h) had the minimum inhibitory concentration (MIC) for escherichia coli (10.42 × 10-6) with the loaded amount of silver of (41.35±0.42)％ (mass fraction).The sterilizing rate of Ag-loaded zeolite to escherichia coli was (98.36±0.28)％,and the diameter of inhibition zone was 15.8 mm.When applying the Ag-loaded zeolite to staphylococcus aureus,the MIC was 12.50 × 10-6,the sterilizing rate was (97.43 ± 0.19)％,and diameter of inhibition zone was 13.6 mm.Meanwhile,the Ag-loaded zeolite had good sustained-release performance and anti-tarnish property.