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Synthesis and Biological Evaluation of Dantrolene-Like Hydrazide and Hydrazone Analogues as Multitarget Agents for Neurodegenerative Diseases |
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| Authors: | Dr Isabella Bolognino Dr Nicola Giangregorio Dr Annamaria Tonazzi Dr Antón L Martínez Prof Cosimo D Altomare Prof María I Loza Dr Sara Sablone Prof Saverio Cellamare Prof Marco Catto |
| Affiliation: | 1. Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy
Department of Engineering and Applied Sciences, University of Bergamo, Viale G. Marconi 5, 24044 Dalmine, Italy These authors contributed equally to this work.;2. Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), National Research Council (CNR), Via Amendola 122/O, 70126 Bari, Italy These authors contributed equally to this work.;3. Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), National Research Council (CNR), Via Amendola 122/O, 70126 Bari, Italy;4. BioFarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University of Santiago de Compostela, Av. Barcelona, Campus Vida, 15782 Santiago de Compostela, Spain;5. Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy;6. Section of Legal Medicine, Interdisciplinary Department of Medicine, Bari Policlinico Hospital, University of Bari Aldo Moro, Piazza Giulio Cesare 11, 70124 Bari, Italy |
| Abstract: | |
| Keywords: | dantrolene analogues hydrazide and hydrazone derivatives multitarget activity carnitine/acylcarnitine carrier Alzheimer's disease |