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A Step toward NRF2-DNA Interaction Inhibitors by Fragment-Based NMR Methods
Authors:Dr Sven Brüschweiler  Dr Julian E Fuchs  Dr Gerd Bader  Dr Darryl B McConnell  Dr Robert Konrat  Dr Moriz Mayer
Affiliation:1. Christian Doppler Laboratory for High-Content Structural Biology and Biotechnology, Department of Structural and Computational Biology, Max Perutz Labs, University of Vienna, Campus Vienna Biocenter 5, 1030 Vienna, Austria;2. Boehringer Ingelheim RCV GmbH & Co. KG, Dr. Boehringer Gasse 5–11, 1121 Vienna, Austria
Abstract:
Keywords:NRF2  protein-DNA interactions  fragment screening  structure-activity relationships  ligand docking  NMR solution structures
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