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Alterations in Kynurenine and NAD+ Salvage Pathways during the Successful Treatment of Inflammatory Bowel Disease Suggest HCAR3 and NNMT as Potential Drug Targets
Authors:Artur Wnorowski  Sylwia Wnorowska  Jacek Kurzepa  Jolanta Parada-Turska
Affiliation:1.Department of Biopharmacy, Medical University of Lublin, 20-093 Lublin, Poland;2.Department of Medical Chemistry, Medical University of Lublin, 20-093 Lublin, Poland; (S.W.); (J.K.);3.Department of Rheumatology and Connective Tissue Diseases, Medical University of Lublin, 20-090 Lublin, Poland;
Abstract:
Keywords:metabolic network reconstruction   G protein-coupled receptor 109B   immune-mediated inflammatory disease   gut inflammation   anti-cytokine monoclonal antibodies   nicotinamide phosphoribosyltransferase
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