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Microneedle Array-Based Platforms for Future Theranostic Applications |
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| Authors: | Olivia Howells Natasha Rajendran Sarah Mcintyre Sara Amini-Asl Pauline Henri Dr Yufei Liu Prof Owen Guy Prof Anthony E G Cass Dr May C Morris Dr Sanjiv Sharma |
| Affiliation: | 1. College of Engineering, Swansea University, Fabian Way, Crymlyn Burrows, Bay Campus, Swansea, SA1 8EN UK;2. Institut des Biomolécules Max Mousseron, UMR 5247, Université de Montpellier, Faculté de Pharmacie, 34093 Montpellier, France;3. Laboratory of Optoelectronic Technology and Systems, Ministry of Education, Centre for Intelligent Sensing Technology, College of Optoelectronic Engineering, Chongqing University, Chongqing, 400044 P. R China;4. Department of Chemistry and Institute of Biomedical Engineering, Imperial College London, Exhibition Road, London, SW7 2AZ UK |
| Abstract: | Theranostics involves finding the biomarkers of a disease, fighting them through site specific drug delivery and following them for prognosis of the disease. Microneedle array technology has been used for drug delivery and extended for continuous monitoring of analytes present in the skin compartment. We envisage the use of microneedle arrays for future theranostic applications. The potential of combining microneedle array-based drug delivery and diagnostics as part of closed-loop control system for the management of diseases and delivery of precision drugs in individual patients is reported in this paper. |
| Keywords: | artificial pancreas microneedle arrays theranostics transdermal delivery |