Affiliation: | 1. Instituto de Investigação do Medicamento (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal These authors contributed equally to this work;2. Division of Clinical Pharmacology, Department of Medicine, Drug Discovery and Development Centre (H3D), University of Cape Town, Observatory, 7925 South Africa;3. Department of Chemistry, South African Medical Research Council Drug Discovery and Development Research Unit, University of Cape Town, Rondebosch, 7701 South Africa;4. Department of Chemistry, University of Cape Town, Rondebosch, 7701 South Africa Department of Chemistry, South African Medical Research Council Drug Discovery and Development Research Unit, University of Cape Town, Rondebosch, 7701 South Africa Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch, 7701 South Africa;5. Instituto de Investigação do Medicamento (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal;6. Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch, 7701 South Africa Department of Pathology, SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, University of Cape Town, Rondebosch, 7701 South Africa Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Rondebosch, 7701 South Africa |