| 对氨基苯甲酸壳聚糖酯的制备、表征及抗菌活性 |
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| 引用本文： | 王河东,王江涛.对氨基苯甲酸壳聚糖酯的制备、表征及抗菌活性[J].功能材料,2011(S5). |
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| 作者姓名： | 王河东 王江涛 |
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| 作者单位： | 中国海洋大学海洋化学理论和工程技术教育部重点实验室; |
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| 基金项目： | 国家自然科学基金资助项目(41076065); 国家重点基础研究发展计划(973计划)资助项目(2010CB428701) |
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| 摘 要： | 壳聚糖(CTS)经氨基保护合成席夫碱,再与由对氨基苯甲酸和氯化亚砜制备的对氨基苯甲酰氯反应,产物在一定pH下氨基去保护得到了对氨基苯甲酸壳聚糖酯(ABCTSE)。产物经FT-IR、1H NMR、13C NMR进行结构表征,证实为目标产物;由元素分析得到所制得壳聚糖酯的酯化度为16.8%、40.4%;室温下,壳聚糖衍生物在蒸馏水及有机试剂中的溶解性比壳聚糖更好;产物的TG和DTG分析结果表明所制得壳聚糖酯的稳定性稍低于壳聚糖。另外,由于分子结构中两个氨基的存在,其溶于弱酸性溶液后随着形成—NH3+的增多,使其在抑菌方面有更大优势。
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| 关 键 词： | 壳聚糖酯 氨基 有机可溶性 抑菌性 |
Synthesize,characterization and antimicrobial activity of neoteric chitosan ester |
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| WANG He-dong,WANG Jiang-tao.Synthesize,characterization and antimicrobial activity of neoteric chitosan ester[J].Journal of Functional Materials,2011(S5). |
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| Authors: | WANG He-dong WANG Jiang-tao |
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| Affiliation: | WANG He-dong,WANG Jiang-tao(Key Laboratory of Marine Chemistry Theory and Technology,Ministry of Education,Ocean University of China,Qingdao 266100,China) |
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| Abstract: | Schiff base of chitosan(BCTS)was obtained by the reaction of chitosan and benzaldehyde,and then BCTS had the reaction with acyl chloride which was synthesized by p-aminobenzoic acid and thionyl chloride.Finally,removing the group of amino protection to get the target product.The structure of the derivatives was characterized by FT-IR,1H NMR,13C NMR;the elemental analysis results indicated that the degrees of substitution of the products were 16.8% and 40.4%.The chitosan derivatives exhibited an better solub... |
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| Keywords: | chitosan ester amino group organic-soluble bacteriostasis |
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