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Copper‐in‐Charcoal‐Catalyzed,Tandem One‐Pot Diazo Transfer‐Click Reactions |
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| Authors: | Ching‐Tien Lee Shenlin Huang Bruce&#x;H Lipshutz |
| Abstract: | Copper‐in‐charcoal (Cu/C) is an effective heterogeneous catalyst for tandem diazo transfer/click reactions. In the presence of Cu/C, various azides can be generated in situ from the corresponding amines, and subsequently undergo 3+2] cycloaddition with terminal alkynes to afford triazoles in good yields. The catalyst is also easily recycled. |
| Keywords: | click chemistry copper‐in‐charcoal diazo transfer heterogeneous catalysis |