Alkynyl Group as Activating Group: Base‐Catalyzed Diastereoselective Domino Reactions of Electron‐Deficient Enynes

This paper describes a base‐catalyzed domino reaction of electron‐deficient enynes with malonate‐derived α,β‐unsaturated esters and ketones, which provides a rapid, stereoselective access to multi‐functionalized cyclopentanes and inden‐5(6 H)‐ones in high yields. In this reaction, the alkynyl group of the enyne acts as an activating group rather than a reacting group.