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Quercetin Reduces Lipid Accumulation in a Cell Model of NAFLD by Inhibiting De Novo Fatty Acid Synthesis through the Acetyl-CoA Carboxylase 1/AMPK/PP2A Axis |
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| Authors: | Antonio Gnoni Benedetta Di Chiara Stanca Laura Giannotti Gabriele Vincenzo Gnoni Luisa Siculella Fabrizio Damiano |
| Affiliation: | 1.Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari “Aldo Moro”, 70121 Bari, Italy;2.Laboratory of Molecular Biology, Department of Biological and Environmental Sciences and Technologies, University of Salento, 73100 Lecce, Italy; (B.D.C.S.); (L.G.); (L.S.);3.Laboratory of Biological Chemistry, Department of Biological and Environmental Sciences and Technologies, University of Salento, 73100 Lecce, Italy; |
| Abstract: | |
| Keywords: | acetyl-CoA carboxylase 1 AMP-activated protein kinase de novo lipogenesis endoplasmic reticulum stress quercetin citrate carrier non-alcoholic fatty liver disease protein phosphatase 2A sterol regulatory element-binding protein 1 |