Human Chorionic Gonadotropin and Early Embryogenesis: Review |
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| Authors: | Sophie Perrier d’ Hauterive,Romann Close,Virginie Gridelet,Marie Mawet,Michelle Nisolle,Vincent Geenen |
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| Abstract: | Human chorionic gonadotropin (hCG) has four major isoforms: classical hCG, hyperglycosylated hCG, free β subunit, and sulphated hCG. Classical hCG is the first molecule synthesized by the embryo. Its RNA is transcribed as early as the eight-cell stage and the blastocyst produces the protein before its implantation. This review synthetizes everything currently known on this multi-effect hormone: hCG levels, angiogenetic activity, immunological actions, and effects on miscarriages and thyroid function. |
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| Keywords: | hCG implantation pregnancy immunology miscarriages thyroid function |
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