| 高效液相色谱法测定氧氟沙星含量的方法改进 |
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| 引用本文： | 李士敏,俞松林,李宝新,袁牧.高效液相色谱法测定氧氟沙星含量的方法改进[J].广州化工,2011(24):104-105. |
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| 作者姓名： | 李士敏 俞松林 李宝新 袁牧 |
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| 作者单位： | 浙江医药高等专科学校药学系;宁波市麦迪逊医药科技有限公司;广州医学院药物研究中心 |
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| 基金项目： | 浙江医药高等专科学校校企合作项目 |
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| 摘 要： | 对高效液相色谱法（HPLC）测定氧氟沙星原料药含量的方法改进。在氧氟沙星原料药含量测定结果与印度药典方法无显著差异条件下,大大缩短了分析时间。本方法快速、准确,更适用于常规检验工作和厂方大批量生产时的质量控制。
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| 关 键 词： | 高效液相色谱 氧氟沙星 含量 方法改进 |
The Improvement in Assaying of the Ofloxacin API by HPLC |
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| LI Shi-min,YU Song-lin,LI Bao-xin,YUAN Mu.The Improvement in Assaying of the Ofloxacin API by HPLC[J].GuangZhou Chemical Industry and Technology,2011(24):104-105. |
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| Authors: | LI Shi-min YU Song-lin LI Bao-xin YUAN Mu |
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| Affiliation: | 1 Zhejiang Pharmaceutical College,Ningbo Zhejiang 315100;2 Ningbo Medicn Pharmaceutical Co.,Ltd., Zhejiang Ningbo 315040;3 Guangzhou Medical University,Guangdong Guangzhou 510182,China) |
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| Abstract: | The high performance liquid chromalograph(HPLC) method for the assaying of the Ofloxacin API.The retention time was shortened and the results had no obvious differences with that of Indian Pharmacopoeia method.The method was rapid,accurate and adapted to routine analysis and quality control in factory better. |
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| Keywords: | HPLC Ofloxacin content methods improvement |
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