一次性纸杯中全氟辛酸 及全氟辛烷磺酸的膳食暴露研究

为了评估不同人群通过一次性纸杯摄入全氟辛酸(PFOA)及全氟辛烷磺酸(PFOS)的风险,采用超高效液相色谱串联质谱法测定一次性纸杯中PFOA及PFOS向不同食品中的迁移量,结合调查所得一次性纸杯的消费数据,利用点评估方法计算PFOA及PFOS通过一次性纸杯向不同人群的急性及慢性暴露量,并评估其急慢性暴露风险。结果表明,20种一次性纸杯中,PFOA及PFOS向食品中的迁移量分别为ND~23.70×10^-3 ng/cm²、ND~4.10×10^-3 ng/cm²;PFOA及PFOS的急性人群暴露量分别为45.67×10^-3~168.36×10^-3 ng/(kg·d)和7.91×10^-3~29.14×10^-3 ng/(kg·d),慢性人群暴露量分别为0.16×10^-3~4.05×10^-3 ng/(kg·d)和0.02×10^-3~0.51×10^-3 ng/(kg·d),均远低于欧盟推荐的每日摄入耐受量。人群通过一次性纸杯摄入PFOA及PFOS的风险处于可接受的水平。

Dietary Exposure to Perfluorooctanoic Acid and Perfluorooctanesulfonic Acid through Disposable Carboard Cups

In order to evaluate the dietary intake risk of PFOA and PFOS through disposable carboard cups for different groups of people,liquid chromatography-tandem mass spectrometry(LC-MS/MS)method was used to determine the migration amount of perfluorooctanoic acid(PFOA)and perfluorooctanesulfonic acid(PFOS)from disposable carboard cups to foods,and the disposable carboard cups consumption data of different groups were investigated. The results showed that migration amounts of PFOA and PFOS from 20 brands of carboard cups to foods were ND~23.70×10-3 ng/cm2,ND~4.10×10-3 ng/cm2,respectively. The acute exposure of PFOA was 45.67×10-3~168.36×10-3 ng/(kg·d),and the acute exposure of PFOS was 7.91×10-3~29.14×10-3 ng/(kg·d). 0.16×10-3~4.05×10-3 ng/(kg·d)and 0.02×10-3~0.51×10-3 ng/(kg·d)were the chronic exposure for PFOA and PFOS. The acute and chronic exposure levels of PFOA and PFOS were far below the tolerable daily intakes established by the Scientific Panel on Contaminants in the Food Chain of the European Union. The dietary intake risks of PFOA and PFOS through consumption of disposable carboard cups for different age groups and genders were acceptable.