磺胺类抗生素分子印迹制备技术与应用进展

分子印迹技术是一种可以特异性地从样品中将待测物分离和富集,降低样品中复杂基质对待测物检测结果的干扰,提高仪器检测精度的前处理技术,现已广泛应用于动物性食品中的兽药残留检测领域。磺胺类抗生素作为最常被检出的兽药之一,其检测方法的优化有着重要研究意义。本文聚焦了近年来磺胺类抗生素分子印迹技术的发展趋势,包括新型功能单体、交联剂和致孔剂的选用,聚合方法的优化以及其应用模式从传统固相萃取材料到快速检测产品的转变,阐述了该技术的优势和目前存在的问题,为磺胺类抗生素分子印迹聚合技术的发展提供参考。

Preparation and Application Progress of Sulfonamides Molecular Imprinting Technology

Molecular imprinting technology (MIT) is a pretreatment technique which can specifically separate and enrich the analyte from the sample, reduce the interference of the complex matrix in the sample, and improve the detection accuracy of the instrument. It has been widely used in the food including meat, milk, and egg, etc. It is rather important to develop the novel detection method for sulfonamides which have been one of the most commonly detected veterinary drugs. This review focuses on the development of sulfonamides molecular imprinting technology in recent years, which includes the selection of new functional monomers, cross-linking agents and porogens, the optimization of surface molecular imprinting polymerization substrates and the transformation from traditional solid-phase extraction materials to rapid detection products. It expounds the advantages and the problems of MIT and provides the reference for the development of sulfonamides molecularly imprinted polymers.