| 膳食多酚改善炎症性肠病的作用机制研究进展 |
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| 引用本文： | 林鹏程,曹峻菡,解万翠. 膳食多酚改善炎症性肠病的作用机制研究进展[J]. 食品与机械, 2021, 0(9): 205-210 |
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| 作者姓名： | 林鹏程 曹峻菡 解万翠 |
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| 作者单位： | 青岛科技大学海洋科学与生物工程学院，山东 青岛 266042;青岛科技大学海洋科学与生物工程学院，山东 青岛 266042；山东省生物化学工程重点实验室，山东 青岛 266042；山东省宏福慧科技有限公司，山东 临沂 276000；尚好科技有限公司，山东 青岛 266002 |
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| 基金项目： | 国家重点研发计划项目（编号：2018YFD0901105） |
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| 摘 要： | 文章概述了膳食多酚通过调节氧化应激、保护肠黏膜屏障、调节肠道菌群及代谢物改善炎症性肠病的作用机制，重点阐述了膳食多酚对炎症性肠病炎症信号通路的调节作用，并展望了膳食多酚在炎症性肠病等疾病营养干预领域的研究方向。
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| 关 键 词： | 多酚；炎症性肠病；营养干预；作用机制；信号通路；调节 |
| 收稿时间： | 2021-03-23 |
Research progress on the mechanism of dietary polyphenols in improving inflammatory bowel disease |
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| LINPengcheng,CAOJunhan,XIEWancui. Research progress on the mechanism of dietary polyphenols in improving inflammatory bowel disease[J]. Food and Machinery, 2021, 0(9): 205-210 |
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| Authors: | LINPengcheng CAOJunhan XIEWancui |
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| Affiliation: | College of Mairine Science and Biological Engineering, Qingdao University of Science & Technology, Qingdao, Shandong 266042, China; College of Mairine Science and Biological Engineering, Qingdao University of Science & Technology, Qingdao, Shandong 266042, China; Key Laboratory for Biochemical Engineering of Shandong Province, Qingdao, Shandong 266042, China; Shandong Searsport Bio-tech Co., Ltd., Linyi, Shandong 276000, China; Shanghao Science and Technology Co., Ltd., Qingdao, Shandong 266002, China |
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| Abstract: | This article summarizes the mechanism by which dietary polyphenols improve inflammatory bowel disease by regulating oxidative stress, protecting the intestinal mucosal barrier, regulating intestinal flora and metabolites, highlights the regulatory effect of dietary polyphenols on inflammatory bowel disease inflammatory signaling pathways, and prospects to the research direction of dietary polyphenols in the nutritional intervention field of inflammatory bowel disease and other diseases. |
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| Keywords: | polyphenols inflammatory bowel disease nutritional intervention mechanism of action signaling pathways regulation |
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