| Effects of β-TCP Ceramics on Intracellular Ca~(2+) Concentration,Mineralization of Osteoblast and Protein Structure |
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| 作者姓名： | 齐志涛 张启焕 |
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| 作者单位： | School of Chemical and Biological Engineering;Yancheng Institute of Technology;The Bio-material Research and Engineering Center;Wuhan University of Technology; |
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| 基金项目： | Funded by the Research Fund of Key Laboratory for Advanced Technology in Environmental Protection of Jiangsu Province (AE201037); the Foundation for Talent Recruitment of Yancheng Institute of Technology (XKR2011007); “973” Chinese National Key Fundamental Research and Development Program (No.G1999064701) |
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| 摘 要： | β-TCP, as one of calcium phosphates ceramics, exerts perfect biocompatibility and osteoconductivity, and is clinically used as a bone graft substitute for decades. Consequently, the effects of β-TCP ceramics on intracellular Ca2+ concentration, mineralization of osteoblast and BSA protein structure were studied. Results showed that β-TCP could increase the intracelluar Ca2+ concentration and mineralization of osteoblast, indicating that β-TCP ceramics could take part in the organic metabolism and the degrad...
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| 关 键 词： | β-TCP ceramics mineralization osteoblast [Ca2 ]i protein structure |
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