| 聚氧化乙烯/海藻酸钠/羟丙基-癸烷基壳聚糖网络凝胶的制备及其对三七总皂苷的体外释放性能研究 |
| |
| 引用本文： | 谭福能.聚氧化乙烯/海藻酸钠/羟丙基-癸烷基壳聚糖网络凝胶的制备及其对三七总皂苷的体外释放性能研究[J].日用化学工业,2018,48(4):205-209. |
| |
| 作者姓名： | 谭福能 |
| |
| 作者单位： | 文山学院化学与工程学院 |
| |
| 基金项目： | 云南省教育厅科学研究基金资助项目(2017ZZX056)；云南省科技厅应用基础研究资助项目(2012FD058） |
| |
| 摘 要： | 将壳聚糖改性成两亲性的羟丙基-癸烷基壳聚糖,并通过化学交联方法制备了聚氧化乙烯/海藻酸钠/羟丙基-癸烷基壳聚糖载药网络凝胶。利用傅利叶变换红外光谱仪、X-射线衍射仪、扫描电子显微镜对凝胶结构进行了表征。实验结果表明,该凝胶具有良好的网状结构和溶胀性,同时兼具p H敏感性和温度敏感性,在不同p H环境中均对三七总皂苷具有一定的缓释作用。
|
| 关 键 词： | 羟丙基-癸烷基壳聚糖 海藻酸钠 聚氧化乙烯 凝胶 三七总皂苷 |
| 收稿时间： | 2017/12/1 0:00:00 |
Preparation of network gel of polyethylene oxide/sodium alginate/hydroxypropyl-decyl chitosan and its behavior for in vitro release of panax notoginseng saponins |
| |
| TAN Fu-neng.Preparation of network gel of polyethylene oxide/sodium alginate/hydroxypropyl-decyl chitosan and its behavior for in vitro release of panax notoginseng saponins[J].China Surfactant Detergent & Cosmetics,2018,48(4):205-209. |
| |
| Authors: | TAN Fu-neng |
| |
| Affiliation: | Chemical and Engineering Institute, Wenshan University, Wenshan, Yunnan 663000, China |
| |
| Abstract: | Amphiphilic hydroxypropyl-decyl chitosan was prepared by modification of chitosan. The drug-loading network gel of polyethylene oxide/sodium alginate/hydroxypropyl-decyl chitosan (PEO/SA/HP-DCCS) were prepared via chemical cross-linking method. The structure of the gel was characterized by FT-IR, XRD and SEM. Results show that this gel has good network structure and swelling property toghether with sensitiveness to pH and temperature. The gel has sustained-release effect on panax notoginseng saponins at different pH values. |
| |
| Keywords: | hydroxypropyl-decyl chitosan sodium alginate polyethylene oxide gel panax notoginseng saponins |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《日用化学工业》浏览原始摘要信息 |
|
点击此处可从《日用化学工业》下载全文 |
