The Extraction of Penicillin G with Aliphatic Amines in Organic Solvents of Different Polarities |
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Authors: | Zhi-Fa Yang Shu-Qiu Yu Jia-Yong Chen |
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Affiliation: | Zhi-Fa Yang,Shu-Qiu Yu,Jia-Yong (Chia-Yung) Chen |
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Abstract: | The equilibrium constants of the extraction, the molar ratios of amines to penicillin G in the extract and the bonding structures of the extracted species were studied with chemical analysis and the absorbance shift of FT-IR spectra of the functional groups in penicillin G. Extraction of penicillin G from the filtrate of fermentation broth indicates that amines will be difficult to use as the industrial solvent for the production of penicillin G because of the poor quality of the final crystalline product obtained and the difficulties involved in the stripping and solvent recovery. |
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Keywords: | solvent extraction penicillin G amines FT-IR spectrum. |
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