Synthesis of phosphorus-containing polymers with potential bioactivity

Phosphorylation of poly(N-vinyl pyrrolidone-co-vinyl amine) and poly(N-vinyl pyrrolidone-co-glycidylcrotonate

1 Systematic name: (2,3-Epoxypropyl)crotonate.

) is realized by Atherton-Todd and Fields-Kabachnik reactions and by the means of direct interaction with phosphorus trichloride and phosphorus trichloride oxide. The composition and structure of the isolated final products was proved by NMR (¹H and ³¹P), IR spectroscopy and elemental analysis.