表面增强拉曼光谱技术在真菌毒素检测中的应用研究进展

表面增强拉曼光谱（surface enhanced raman spectroscopy，SERS）是一种新型的快速检测技术，能通过增强基底灵敏探测化合物的分子指纹信息，从而清楚解析其特征化学结构，具有样本前处理简单、检测速度快、灵敏度高、光谱信息丰富、易操作等优点，在食源性真菌毒素的检测领域有很大的应用价值。本文介绍了表面增强拉曼光谱技术的发展历程、增强机理、基底的分类以及检测模式，综述了近5年在食品中真菌毒素快速检测方面的最新研究进展，并提出了亟待解决的问题和发展趋势，旨在为今后SERS技术的研究和开发提供帮助。

Research Progress of Surface Enhanced Raman Spectroscopy in the Detection of Mycotoxins

Surface-enhanced Raman spectroscopy(SERS)is a new type of rapid detection technology.By enhancing the substrate,it can sensitively detect the molecular fingerprint information of a compound,so as to clearly resolve its characteristic chemical structure.It has the advantages of simple sample preparation,fast detection speed,high sensitivity,rich spectral information and easy operation.It has great application value in the field of food-borne mycotoxin detection.This article introduces the development history,enhancement mechanism,substrate classification and detection mode of surface-enhanced Raman spectroscopy,it summarizes the latest research progress in the rapid detection of mycotoxins in food in the past 5 years,and puts forward the problems and development trends that need to be solved urgently,aiming to provide assistance for the research and development of SERS technology in the future.