Magnetic Particle Imaging: Current and Future Applications,Magnetic Nanoparticle Synthesis Methods and Safety Measures |
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| Authors: | Caroline Billings Mitchell Langley Gavin Warrington Farzin Mashali Jacqueline Anne Johnson |
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| Affiliation: | 1.College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996, USA;2.Department of Mechanical, Aerospace and Biomedical Engineering, University of Tennessee, Knoxville, TN 37996, USA; (M.L.); (G.W.); (F.M.);3.Department of Mechanical, Aerospace and Biomedical Engineering, University of Tennessee Space Institute, Tullahoma, TN 37388, USA |
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| Abstract: | Magnetic nanoparticles (MNPs) have a wide range of applications; an area of particular interest is magnetic particle imaging (MPI). MPI is an imaging modality that utilizes superparamagnetic iron oxide particles (SPIONs) as tracer particles to produce highly sensitive and specific images in a broad range of applications, including cardiovascular, neuroimaging, tumor imaging, magnetic hyperthermia and cellular tracking. While there are hurdles to overcome, including accessibility of products, and an understanding of safety and toxicity profiles, MPI has the potential to revolutionize research and clinical biomedical imaging. This review will explore a brief history of MPI, MNP synthesis methods, current and future applications, and safety concerns associated with this newly emerging imaging modality. |
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| Keywords: | magnetic nanoparticles magnetic particle imaging superparamagnetic iron oxide nanoparticle safety |
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