米糠粗多糖对小鼠免疫调节功能影响研究

以脱脂米糠为原料提取四种多糖:高温及低温条件下蒸馏水提取水溶性多糖(HWSRBP、LWSRBP)、稀碱提取水溶性多糖(ASRBP)和稀碱提取水不溶性多糖(AISRBP)。采用小鼠灌胃实验,观察四种米糠多糖对正常小鼠免疫功能调节作用。结果表明:高、中剂量高温水提取米糠多糖、碱提水溶性米糠多糖能显著增强正常小鼠脾淋巴细胞增殖能力,增强正常小鼠腹腔巨噬细胞吞噬鸡红细胞能力,按照保健食品免疫调节作用评价程序规定,认为高温水提取米糠多糖、碱提水溶性米糠多糖对小鼠免疫功能具有调节作用。

Investigation on Immunomodulating Activities of Rice Bran Polysaccharides in Mice

Hot water-soluble crude polysaccharide (HWSRBP), cool water-soluble crude poly-saccharide (LWSRBP),Alkaline-soluble crude polysaccharide (ASRBP) and Alkaline-insoluble crude polysaccharide (AISRBP) were obtained from defatted rice bran. As compared with the control group, WSRBP and ASRBP had significant stimulating effects on all indexes such as the Spleen index; Thymus index; T lymphocyte proliferation induced by Con A; the phagocytosis function of ma-crophages abdominal cavities by oral administration in natural mice. The result indicated that rice bran polysaccharides WSRBP and ASRBP have imunomodulating functions in animals and can be used as a supplement for immune enhancement system.