Quantum dot encapsulation in viral capsids |
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| Authors: | Dixit Suraj K Goicochea Nancy L Daniel Marie-Christine Murali Ayaluru Bronstein Lyudmila De Mrinmoy Stein Barry Rotello Vincent M Kao C Cheng Dragnea Bogdan |
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| Affiliation: | Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA. |
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| Abstract: | Incorporation of CdSe/ZnS semiconductor quantum dots (QDs) into viral particles provides a new paradigm for the design of intracellular microscopic probes and vectors. Several strategies for the incorporation of QDs into viral capsids were explored; those functionalized with poly(ethylene glycol) (PEG) can be self-assembled into viral particles with minimal release of photoreaction products and enhanced stability against prolonged irradiation. |
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